Loss of the H3K9 methyltransferase G9a in skin cancer increases tumour aggressiveness.

See Avgustinova et al.

Avoiding a tug-of-war for IFT transport

See Jordan et al.

A local inhibitor of Scar/Wave at the leading edge

See Fort et al.

Focusing on Women in Science

See Focus

Embryo structures assembled from three cell types

See Sozen et al.

Transmission electron micrograph of a mitochondrion.

See Reviews by Haigis and Hajnóczky

The mammary gland develops from embryonic multipotent progenitors that switch to unipotency and express a unique gene signature.

See Wuidart et al., the related Lilja et al. and News & Views by Howard

XMAP215 acts together with γ-tubulin ring complex (γ-TURC) to nucleate microtubules, challenging the view that γ-TURC alone is the universal nucleator

See Thawani et al. and News & Views by Lüders

Embryonic fibroblast lineages do not express Engrailed and mediate early dermal development, whereas Engrailed-expressing fibroblasts induce scarring in adults.

See Jiang et al. and News & Views by Yokoyama & Rafi

Isolating intact mitochondria from specific cells shows that the Caenorhabditis elegans germline propagates deleterious mitochondrial genomes.

See Ahier et al.

The EXD2 nuclease localizes to mitochondria and promotes mitochondrial translation, with its loss causing developmental delay and lifespan extension in flies.

See Silva et al.

Migrating cells sense and respond to tissue mechanics and, in turn, modify their surroundings.

See Friedl et al.