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Modelling microtubule patterns

Nature Cell Biology volume 8, pages 1204–1211 (2006)Cite this article

Abstract

The cellular cytoskeleton is well studied in terms of its biological and physical properties, making it an attractive subject for systems approaches. Here, we describe the experimental and theoretical strategies used to study the collective behaviour of microtubules and motors. We illustrate how this led to the beginning of an understanding of dynamic cellular patterns that have precise functions.

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Figure 1: Different levels of modelling the microtubule motor system.
Figure 2: Models for the motor stepping mechanism.
Figure 3: Standard model elements.
Figure 4: Mean-field methods.

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  1. the European Molecular Systems Biology Laboratory, Meyerhofstrasse 1, Heidelberg, 69117, Germany

    Eric Karsenti, François Nédélec & Thomas Surrey

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  1. Eric Karsenti
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Karsenti, E., Nédélec, F. & Surrey, T. Modelling microtubule patterns. Nat Cell Biol 8, 1204–1211 (2006). https://doi.org/10.1038/ncb1498

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