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The myosin-II-responsive focal adhesion proteome: a tour de force?

Nature Cell Biology volume 13, pages 344–346 (2011)Cite this article

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The formation and maturation of focal adhesions involves significant changes in protein composition and requires acto-myosin contractility. A mass spectrometry approach reveals changes to the focal adhesion proteome on myosin inhibition, providing a valuable resource for the cell adhesion field.

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Figure 1: Focal adhesion protein composition is altered by myosin-II-mediated contractility.

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Authors and Affiliations

  1. Mei Rosa Ng and Joan S. Brugge are in the Department of Cell Biology, Lisa Gallegos, Harvard Medical School, Boston Massachusetts, USA,

    Lisa Gallegos, Mei Rosa Ng & Joan S. Brugge

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  1. Lisa Gallegos
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  2. Mei Rosa Ng
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  3. Joan S. Brugge
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Correspondence to Joan S. Brugge.

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The authors declare no competing financial interests.

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Gallegos, L., Ng, M. & Brugge, J. The myosin-II-responsive focal adhesion proteome: a tour de force?. Nat Cell Biol 13, 344–346 (2011). https://doi.org/10.1038/ncb2230

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