Articles

  • Article |

    Activating transcription factor 4 (ATF4) promotes MYC-driven tumour progression. Tameire et al. identify ATF4 and its target eukaryotic translation initiation factor 4E-binding protein 1 (4E-BP1) as regulators of MYC-mediated amino acid biosynthesis and protein synthesis, thereby modulating tumour progression and survival in mice.

    • Feven Tameire
    • , Ioannis I. Verginadis
    • , Nektaria Maria Leli
    • , Christine Polte
    • , Crystal S. Conn
    • , Rani Ojha
    • , Carlo Salas Salinas
    • , Frank Chinga
    • , Alexandra. M. Monroy
    • , Weixuan Fu
    • , Paul Wang
    • , Andrew Kossenkov
    • , Jiangbin Ye
    • , Ravi K. Amaravadi
    • , Zoya Ignatova
    • , Serge Y. Fuchs
    • , J. Alan Diehl
    • , Davide Ruggero
    •  & Constantinos Koumenis
  • Article |

    Janiszewska et al. show that minor subpopulations expressing IL11 and FIGF in breast cancer cells promote metastasis through altering local and systemic tumour microenvironments including neutrophils.

    • Michalina Janiszewska
    • , Doris P. Tabassum
    • , Zafira Castaño
    • , Simona Cristea
    • , Kimiyo N. Yamamoto
    • , Natalie L. Kingston
    • , Katherine C. Murphy
    • , Shaokun Shu
    • , Nicholas W. Harper
    • , Carlos Gil Del Alcazar
    • , Maša Alečković
    • , Muhammad B. Ekram
    • , Ofir Cohen
    • , Minsuk Kwak
    • , Yuanbo Qin
    • , Tyler Laszewski
    • , Adrienne Luoma
    • , Andriy Marusyk
    • , Kai W. Wucherpfennig
    • , Nikhil Wagle
    • , Rong Fan
    • , Franziska Michor
    • , Sandra S. McAllister
    •  & Kornelia Polyak
  • Article |

    Tian et al. report that the chromatin-related factor Whsc1 regulates the exit from pluripotency and germ layer specification of mouse embryonic stem cells by binding to enhancers of mesendodermal regulators.

    • Tian V. Tian
    • , Bruno Di Stefano
    • , Grégoire Stik
    • , Maria Vila-Casadesús
    • , José Luis Sardina
    • , Enrique Vidal
    • , Alessandro Dasti
    • , Carolina Segura-Morales
    • , Luisa De Andrés-Aguayo
    • , Antonio Gómez
    • , Johanna Goldmann
    • , Rudolf Jaenisch
    •  & Thomas Graf
  • Article |

    Sigal et al. report that Rspo3 regulates Lgr5 cells in the gastric gland base, induces their differentiation into secretory cells and stimulates epithelial antimicrobial defence against H. pylori infection.

    • Michael Sigal
    • , Maria del Mar Reinés
    • , Stefanie Müllerke
    • , Cornelius Fischer
    • , Marta Kapalczynska
    • , Hilmar Berger
    • , Elvira R. M. Bakker
    • , Hans-Joachim Mollenkopf
    • , Michael E. Rothenberg
    • , Bertram Wiedenmann
    • , Sascha Sauer
    •  & Thomas F. Meyer
  • Article |

    Clancy et al. delineate a pathway for pre-miRNA delivery into nascent extracellular vesicles released from tumour cells and show that shed vesicles contain machinery allowing cell-free pre-miRNA processing.

    • James W. Clancy
    • , Ye Zhang
    • , Colin Sheehan
    •  & Crislyn D’Souza-Schorey
  • Article |

    Gao, Nowak-Imialek, Chen et al. generate porcine and human stem cells that possess expanded developmental potency for both embryonic and extra-embryonic cell lineages.

    • Xuefei Gao
    • , Monika Nowak-Imialek
    • , Xi Chen
    • , Dongsheng Chen
    • , Doris Herrmann
    • , Degong Ruan
    • , Andy Chun Hang Chen
    • , Melanie A. Eckersley-Maslin
    • , Shakil Ahmad
    • , Yin Lau Lee
    • , Toshihiro Kobayashi
    • , David Ryan
    • , Jixing Zhong
    • , Jiacheng Zhu
    • , Jian Wu
    • , Guocheng Lan
    • , Stoyan Petkov
    • , Jian Yang
    • , Liliana Antunes
    • , Lia S. Campos
    • , Beiyuan Fu
    • , Shengpeng Wang
    • , Yu Yong
    • , Xiaomin Wang
    • , Song-Guo Xue
    • , Liangpeng Ge
    • , Zuohua Liu
    • , Yong Huang
    • , Tao Nie
    • , Peng Li
    • , Donghai Wu
    • , Duanqing Pei
    • , Yi Zhang
    • , Liming Lu
    • , Fengtang Yang
    • , Susan J. Kimber
    • , Wolf Reik
    • , Xiangang Zou
    • , Zhouchun Shang
    • , Liangxue Lai
    • , Azim Surani
    • , Patrick P. L. Tam
    • , Asif Ahmed
    • , William Shu Biu Yeung
    • , Sarah A. Teichmann
    • , Heiner Niemann
    •  & Pentao Liu
  • Article |

    Cleveland and colleagues report a DNA-replication-dependent error correction mechanism that acts in S phase to remove ectopically loaded CENP-A outside the centromeres, while retaining centromere-bound CENP-A.

    • Yael Nechemia-Arbely
    • , Karen H. Miga
    • , Ofer Shoshani
    • , Aaron Aslanian
    • , Moira A. McMahon
    • , Ah Young Lee
    • , Daniele Fachinetti
    • , John R. Yates III
    • , Bing Ren
    •  & Don W. Cleveland
  • Article |

    Wang et al. map early cardiopharyngeal development in the chordate model Ciona and show that FGF–MAPK signalling maintains multipotency and promotes pharyngeal muscle fate, whereas Tbx1/10-Dach specify second heart lineage identity.

    • Wei Wang
    • , Xiang Niu
    • , Tim Stuart
    • , Estelle Jullian
    • , William M. Mauck III
    • , Robert G. Kelly
    • , Rahul Satija
    •  & Lionel Christiaen
  • Article |

    Grainger et al. demonstrate that, in zebrafish and human cells, EGFR-mediated phosphorylation of Fzd9b promotes internalization of the Wnt9a–Fzd9b–LRP signalosome and subsequent signal transduction.

    • Stephanie Grainger
    • , Nicole Nguyen
    • , Jenna Richter
    • , Jordan Setayesh
    • , Brianna Lonquich
    • , Chet Huan Oon
    • , Jacob M. Wozniak
    • , Rocio Barahona
    • , Caramai N. Kamei
    • , Jack Houston
    • , Marvic Carrillo-Terrazas
    • , Iain A. Drummond
    • , David Gonzalez
    • , Karl Willert
    •  & David Traver
  • Article |

    Carreras-Sureda et al. uncover a non-canonical role for IRE1α as a scaffold that stabilizes InsP3Rs at MAMs to control calcium uptake, fine-tunes ER–mitochondrial communication and regulates energy metabolism via AMPK.

    • Amado Carreras-Sureda
    • , Fabián Jaña
    • , Hery Urra
    • , Sylvere Durand
    • , David E. Mortenson
    • , Alfredo Sagredo
    • , Galdo Bustos
    • , Younis Hazari
    • , Eva Ramos-Fernández
    • , Maria L. Sassano
    • , Philippe Pihán
    • , Alexander R. van Vliet
    • , Matías González-Quiroz
    • , Angie K. Torres
    • , Cheril Tapia-Rojas
    • , Martijn Kerkhofs
    • , Rubén Vicente
    • , Randal J. Kaufman
    • , Nibaldo C. Inestrosa
    • , Christian Gonzalez-Billault
    • , R. Luke Wiseman
    • , Patrizia Agostinis
    • , Geert Bultynck
    • , Felipe A. Court
    • , Guido Kroemer
    • , J. César Cárdenas
    •  & Claudio Hetz
  • Article |

    Necroptosis drives arthritis. Polykratis et al. show that the deubiquitinating enzyme A20 inhibits inflammasome-dependent arthritis development by regulating macrophage necroptosis and this function depends on its ZnF7 ubiquitin binding domain.

    • Apostolos Polykratis
    • , Arne Martens
    • , Remzi Onur Eren
    • , Yoshitaka Shirasaki
    • , Mai Yamagishi
    • , Yoshifumi Yamaguchi
    • , Sotaro Uemura
    • , Masayuki Miura
    • , Bernhard Holzmann
    • , George Kollias
    • , Marietta Armaka
    • , Geert van Loo
    •  & Manolis Pasparakis
  • Article |

    Gan et al. identify the GPCR-like protein GPR137B that interacts with Rag GTPases to recruit mTORC1 to lysosomes. They show that GPR137B controls dynamic Rag and mTORC1 activity as well as lysosome morphology.

    • Lin Gan
    • , Akiko Seki
    • , Kimberle Shen
    • , Harini Iyer
    • , Kyuho Han
    • , Arnold Hayer
    • , Roy Wollman
    • , Xuecai Ge
    • , Jerry R. Lin
    • , Gautam Dey
    • , William S. Talbot
    •  & Tobias Meyer
  • Article |

    Atlasi et al. demonstrate that transcriptome and epigenome resetting during serum-to-2i pluripotency conversion involves minimal enhancer–promoter rewiring and is instead linked to 2i-enhancer activation via Esrrb-mediated H3K27 acetylation.

    • Yaser Atlasi
    • , Wout Megchelenbrink
    • , Tianran Peng
    • , Ehsan Habibi
    • , Onkar Joshi
    • , Shuang-Yin Wang
    • , Cheng Wang
    • , Colin Logie
    • , Ina Poser
    • , Hendrik Marks
    •  & Hendrik G. Stunnenberg
  • Article |

    Smith et al demonstrate that mutated splicing factor U2AF1 promotes expression of a longer isoform of IRAK4, leading to enhanced NF-kB activation and leukaemic growth in acute myeloid leukaemia.

    • Molly A. Smith
    • , Gaurav S. Choudhary
    • , Andrea Pellagatti
    • , Kwangmin Choi
    • , Lyndsey C. Bolanos
    • , Tushar D. Bhagat
    • , Shanisha Gordon-Mitchell
    • , Dagny Von Ahrens
    • , Kith Pradhan
    • , Violetta Steeples
    • , Sanghyun Kim
    • , Ulrich Steidl
    • , Matthew Walter
    • , Iain D. C. Fraser
    • , Aishwarya Kulkarni
    • , Nathan Salomonis
    • , Kakajan Komurov
    • , Jacqueline Boultwood
    • , Amit Verma
    •  & Daniel T. Starczynowski
  • Article |

    Esposito et al. report a role for bone vascular niche E-selectin in promoting mesenchymal–epithelial transition and Wnt signalling in breast cancer cells, thereby enhancing bone metastasis.

    • Mark Esposito
    • , Nandini Mondal
    • , Todd M. Greco
    • , Yong Wei
    • , Chiara Spadazzi
    • , Song-Chang Lin
    • , Hanqiu Zheng
    • , Corey Cheung
    • , John L. Magnani
    • , Sue-Hwa Lin
    • , Ileana M. Cristea
    • , Robert Sackstein
    •  & Yibin Kang
  • Article |

    Unlike many other formin actin assembly factors, INF2 is not autoinhibited. Higgs and colleagues find that INF2 is inhibited by cyclase-associated protein and acetylated actin through a mechanism they name facilitated autoinhibition.

    • Mu A
    • , Tak Shun Fung
    • , Arminja N. Kettenbach
    • , Rajarshi Chakrabarti
    •  & Henry N. Higgs
  • Article |

    Chen et al. show that tumour-associated macrophages transmit HIF-1α-stabilizing long noncoding RNA through extracellular vesicles to breast cancer cells, thereby enhancing tumour glycolysis and chemoresistance.

    • Fei Chen
    • , Jianing Chen
    • , Linbin Yang
    • , Jiang Liu
    • , Xiaoqian Zhang
    • , Yin Zhang
    • , Qingqiang Tu
    • , Dong Yin
    • , Dechen Lin
    • , Ping-Pui Wong
    • , Di Huang
    • , Yue Xing
    • , Jinghua Zhao
    • , Mengfeng Li
    • , Qiang Liu
    • , Fengxi Su
    • , Shicheng Su
    •  & Erwei Song
  • Article |

    Nguyen et al. show that neuropsin (OPN5) suppresses hyaloid vessel regression in the developing mouse retina in response to light, by regulation of the dopamine reuptake transporter and DRD2-dependent suppression of VEGFR2 activity.

    • Minh-Thanh T. Nguyen
    • , Shruti Vemaraju
    • , Gowri Nayak
    • , Yoshinobu Odaka
    • , Ethan D. Buhr
    • , Nuria Alonzo
    • , Uyen Tran
    • , Matthew Batie
    • , Brian A. Upton
    • , Martin Darvas
    • , Zbynek Kozmik
    • , Sujata Rao
    • , Rashmi S. Hegde
    • , P. Michael Iuvone
    • , Russell N. Van Gelder
    •  & Richard A. Lang
  • Article |

    Boos et al. show that impairing mitochondrial protein import induces a global transcriptional response to activate the ubiquitin–proteasome system and heat stress response and repress oxidative phosphorylation genes.​

    • Felix Boos
    • , Lena Krämer
    • , Carina Groh
    • , Ferris Jung
    • , Per Haberkant
    • , Frank Stein
    • , Florian Wollweber
    • , Adrian Gackstatter
    • , Eva Zöller
    • , Martin van der Laan
    • , Mikhail M. Savitski
    • , Vladimir Benes
    •  & Johannes M. Herrmann
  • Article |

    Choi et al. show that the stability of nuclear stress-activated wild-type and mutant p53 is regulated by the type I phosphatidylinositol phosphate kinase PIPK1-α and the lipid messenger PtdIns(4,5)P2.

    • Suyong Choi
    • , Mo Chen
    • , Vincent L. Cryns
    •  & Richard A. Anderson
  • Article |

    Salvagno et al. demonstrated that blocking tumour-associated macrophages in breast cancer enhances the efficacy of chemotherapeutics by promoting intratumoural type I interferon responses.

    • Camilla Salvagno
    • , Metamia Ciampricotti
    • , Sander Tuit
    • , Cheei-Sing Hau
    • , Antoinette van Weverwijk
    • , Seth B. Coffelt
    • , Kelly Kersten
    • , Kim Vrijland
    • , Kevin Kos
    • , Thomas Ulas
    • , Ji-Ying Song
    • , Chia-Huey Ooi
    • , Dominik Rüttinger
    • , Philippe A. Cassier
    • , Jos Jonkers
    • , Joachim L. Schultze
    • , Carola H. Ries
    •  & Karin E. de Visser
  • Article |

    Zhao et al. find that AMPK phosphorylates and activates the mitochondrial Ca2+ uniporter in response to low energy status in mitosis, allowing Ca2+ entry into mitochondria to boost mitochondrial respiration.

    • Haixin Zhao
    • , Teng Li
    • , Kai Wang
    • , Fei Zhao
    • , Jiayi Chen
    • , Guang Xu
    • , Jie Zhao
    • , Ting Li
    • , Liang Chen
    • , Lin Li
    • , Qing Xia
    • , Tao Zhou
    • , Hui-Yan Li
    • , Ai-Ling Li
    • , Toren Finkel
    • , Xue-Min Zhang
    •  & Xin Pan
  • Article |

    Şentürk et al. show that ubiquilins bind v-ATPase to control lysosome acidity, mTOR signalling and autophagic flux in neurons, and that feeding flies with acidic nanoparticles ameliorates defective autophagy in ubiquilin mutants.

    • Mümine Şentürk
    • , Guang Lin
    • , Zhongyuan Zuo
    • , Dongxue Mao
    • , Emma Watson
    • , Antonios G. Mikos
    •  & Hugo J. Bellen
  • Article |

    Nacarelli et al. show that the nicotinamide-phosphoribosyltransferase-regulated NAD+ biogenesis pathway promotes the proinflammatory senescence-associated secretory phenotype by enhancing glycolysis and mitochondrial respiration during senescence.

    • Timothy Nacarelli
    • , Lena Lau
    • , Takeshi Fukumoto
    • , Joseph Zundell
    • , Nail Fatkhutdinov
    • , Shuai Wu
    • , Katherine M. Aird
    • , Osamu Iwasaki
    • , Andrew V. Kossenkov
    • , David Schultz
    • , Ken-ichi Noma
    • , Joseph A. Baur
    • , Zachary Schug
    • , Hsin-Yao Tang
    • , David W. Speicher
    • , Gregory David
    •  & Rugang Zhang
  • Article |

    Liu et al. show that the adaptive branch of unfolded protein response signalling, IRE1α–XBP1, protects haematopoietic stem cells and N-Ras pre-leukaemic stem cells from endoplasmic reticulum stress-induced apoptosis and supports their self-renewal.

    • Lu Liu
    • , Meiling Zhao
    • , Xi Jin
    • , Gina Ney
    • , Kevin B Yang
    • , Fanglue Peng
    • , Jin Cao
    • , Takao Iwawaki
    • , Juan Del Valle
    • , Xi Chen
    •  & Qing Li
  • Article |

    Moro et al. discover an Argonaute 2 (Ago2)-dependent miRNA network that, in response to substrate stiffness, regulates genes involved in tissue mechanics, and show that Ago2 restrains stiffness and contributes to regeneration in the zebrafish fin fold.

    • Albertomaria Moro
    • , Tristan P. Driscoll
    • , Liana C. Boraas
    • , William Armero
    • , Dionna M. Kasper
    • , Nicolas Baeyens
    • , Charlene Jouy
    • , Venkatesh Mallikarjun
    • , Joe Swift
    • , Sang Joon Ahn
    • , Donghoon Lee
    • , Jing Zhang
    • , Mengting Gu
    • , Mark Gerstein
    • , Martin Schwartz
    •  & Stefania Nicoli
  • Article |

    Romani et al. identify a response to reduced actomyosin contractility involving inhibition of Lipin-1, accumulation of SREBP transcription factors at the Golgi apparatus and activation of SREBP transcription driving increased lipid synthesis.

    • Patrizia Romani
    • , Irene Brian
    • , Giulia Santinon
    • , Arianna Pocaterra
    • , Matteo Audano
    • , Silvia Pedretti
    • , Samuel Mathieu
    • , Mattia Forcato
    • , Silvio Bicciato
    • , Jean-Baptiste Manneville
    • , Nico Mitro
    •  & Sirio Dupont
  • Article |

    Wang et al. show that Akt methylation by SETDB1 is recognized by demethylase JMJD2A, which then recruits E3 ligases to induce K63-linked Akt ubiquitination, leading to Akt activation and tumorigenesis.

    • Guihua Wang
    • , Jie Long
    • , Yuan Gao
    • , Weina Zhang
    • , Fei Han
    • , Chuan Xu
    • , Li Sun
    • , Shun-Chin Yang
    • , Jingqin Lan
    • , Zhenlin Hou
    • , Zhen Cai
    • , Guoxiang Jin
    • , Che-Chia Hsu
    • , Yu-Hui Wang
    • , Junbo Hu
    • , Tsai-Yu Chen
    • , Hongyu Li
    • , Min Gyu Lee
    •  & Hui-Kuan Lin
  • Article |

    Guo et al. identify SETDB1 and KDM4B as the methyltransferase and demethylase, respectively, for AKT. AKT methylation promotes its kinase activity and the subsequent tumorigenesis.

    • Jianping Guo
    • , Xiangpeng Dai
    • , Benoit Laurent
    • , Nana Zheng
    • , Wenjian Gan
    • , Jian Zhang
    • , Ailan Guo
    • , Min Yuan
    • , Pengda Liu
    • , John M. Asara
    • , Alex Toker
    • , Yang Shi
    • , Pier Paolo Pandolfi
    •  & Wenyi Wei
  • Article |

    Li et al. show that the epithelial–mesenchymal-transition transcription factor Snail induces claudin-11 expression and suppresses RhoA activity, thereby promoting collective migration and tumour progression in head and neck cancer.

    • Ching-Fei Li
    • , Jia-Yang Chen
    • , Yang-Hui Ho
    • , Wen-Hao Hsu
    • , Liang-Chun Wu
    • , Hsin-Yi Lan
    • , Dennis Shin-Shian Hsu
    • , Shyh-Kuan Tai
    • , Ying-Chih Chang
    •  & Muh-Hwa Yang
  • Article |

    Zhang et al. show that ALK phosphorylates SMAD4 at Tyr 95 to block its binding to DNA, representing a mutation-independent mechanism for blocking the tumour suppressor function of TGF-β in ALK-positive cancers.

    • Qianting Zhang
    • , Mu Xiao
    • , Shuchen Gu
    • , Yongxian Xu
    • , Ting Liu
    • , Hao Li
    • , Yi Yu
    • , Lan Qin
    • , Yezhang Zhu
    • , Fenfang Chen
    • , Yulong Wang
    • , Chen Ding
    • , Hongxing Wu
    • , Hongbin Ji
    • , Zhe Chen
    • , Youli Zu
    • , Stephen Malkoski
    • , Yi Li
    • , Tingbo Liang
    • , Junfang Ji
    • , Jun Qin
    • , Pinglong Xu
    • , Bin Zhao
    • , Li Shen
    • , Xia Lin
    •  & Xin-Hua Feng
  • Article |

    Carlson et al. show that DTCs within the PVN are protected from chemotherapy; targeting interactions between DTCs and the PVN enhances chemosensitivity and prevents bone metastasis.

    • Patrick Carlson
    • , Arko Dasgupta
    • , Candice A. Grzelak
    • , Jeanna Kim
    • , Alexander Barrett
    • , Ilsa M. Coleman
    • , Ryann E. Shor
    • , Erica T. Goddard
    • , Jinxiang Dai
    • , Emma M. Schweitzer
    • , Andrea R. Lim
    • , Sarah B. Crist
    • , David A. Cheresh
    • , Peter S. Nelson
    • , Kirk C. Hansen
    •  & Cyrus M. Ghajar
  • Article |

    Performing a small-molecule screen, Liu et al. identify IRAK as a regulator of PIDDosome activity and tumour radioresistance, and demonstrate a synergistic effect of targeting IRAK1 and PIN1 in response to ionizing radiation.

    • Peter H. Liu
    • , Richa B. Shah
    • , Yuanyuan Li
    • , Arshi Arora
    • , Peter Man-Un Ung
    • , Renuka Raman
    • , Andrej Gorbatenko
    • , Shingo Kozono
    • , Xiao Zhen Zhou
    • , Vincent Brechin
    • , John M. Barbaro
    • , Ruth Thompson
    • , Richard M. White
    • , Julio A. Aguirre-Ghiso
    • , John V. Heymach
    • , Kun Ping Lu
    • , Jose M. Silva
    • , Katherine S. Panageas
    • , Avner Schlessinger
    • , Robert G. Maki
    • , Heath D. Skinner
    • , Elisa de Stanchina
    •  & Samuel Sidi
  • Article |

    Keklikoglou et al. report that cytotoxic drugs induce tumour-derived extracellular vesicles that facilitate monocyte expansion through annexin A6 and thus lung metastasis in breast cancer.

    • Ioanna Keklikoglou
    • , Chiara Cianciaruso
    • , Esra Güç
    • , Mario Leonardo Squadrito
    • , Laura M. Spring
    • , Simon Tazzyman
    • , Lore Lambein
    • , Amanda Poissonnier
    • , Gino B. Ferraro
    • , Caroline Baer
    • , Antonino Cassará
    • , Alan Guichard
    • , M. Luisa Iruela-Arispe
    • , Claire E. Lewis
    • , Lisa M. Coussens
    • , Aditya Bardia
    • , Rakesh K. Jain
    • , Jeffrey W. Pollard
    •  & Michele De Palma
  • Article |

    Avgustinova et al. report that targeting the H3K9 methyltransferase G9a in skin cancer does not affect single nucleotide variant profiles, but leads to increased tumour aggressiveness after a prolonged latency.

    • Alexandra Avgustinova
    • , Aikaterini Symeonidi
    • , Andrés Castellanos
    • , Uxue Urdiroz-Urricelqui
    • , Llorenç Solé-Boldo
    • , Mercè Martín
    • , Ivan Pérez-Rodríguez
    • , Neus Prats
    • , Ben Lehner
    • , Fran Supek
    •  & Salvador Aznar Benitah
  • Article |

    Lafont et al. uncover a checkpoint mediated by TBK1 and IKKε, which phosphorylate RIPK1 in the TNFR1-SC. TBK1 and IKKε recruitment depends on M1 ubiquitylation and NEMO to restrict TNF-induced cell death.

    • Elodie Lafont
    • , Peter Draber
    • , Eva Rieser
    • , Matthias Reichert
    • , Sebastian Kupka
    • , Diego de Miguel
    • , Helena Draberova
    • , Anne von Mässenhausen
    • , Amandeep Bhamra
    • , Stephen Henderson
    • , Katarzyna Wojdyla
    • , Avigayil Chalk
    • , Silvia Surinova
    • , Andreas Linkermann
    •  & Henning Walczak