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Endothelin signalling drives dermal sheath smooth muscle contraction for hair follicle regression
Contraction of the hair follicle-lining dermal sheath smooth muscle generates the forces necessary for the tissue remodelling that takes place during the regression phase of the hair growth cycle. This study reveals that endothelin signalling — from epithelial progenitors at the follicle bottleneck region to its neighbouring dermal sheath — is the main contraction-activating pathway.
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Methods for studying noncoding RNA
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EMBO | EMBL Symposium: Brain genome: regulation, evolution and function
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EMBO | EMBL Symposium: The human microbiome
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EMBL Conference: Protein synthesis and translational control
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Neurodegeneration: New Biology Guiding the Next Generation of Therapeutic Development
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Innate Immunity: From Innate Sensing to Adaptive Responses