Cells in multicolor

Spatiotemporal dynamics of membrane surface charge regulates cell polarity and migration

  • Tatsat Banerjee
  • Debojyoti Biswas
  • Peter N. Devreotes


  • Artistic rendition of metabolic signaling

    Join us November 1, 2022—November 3, 2022 for a virtual meeting presented by Nature Cell Biology, Nature Reviews Molecular and Cell Biology, and Nature Metabolism. We are pleased to bring together experts from diverse fields to discuss recent advances in understanding metabolic signalling pathways in organelles, cells, and tissues, and how these come together to control systemic metabolism.

  • A swirl of cells in brightly contrasting colors

    In this collection, we highlight recent papers published across Nature Portfolio journals on topics including embryonic development and stem cells, clinical and translational research, stem cell-based tissue engineering, and tissue stem cells.

  • To address health disparities and facilitate increasingly personalized treatments, Horwitz, Riley, Millan & Gunawardane call for the development of new models for basic and disease research that reflect diverse ancestral backgrounds and sex, and for the inclusion of diverse populations among donors and research participants.

  • Developing embryos and organs

    In this Focus, we highlight progress in the use of single-cell technologies to analyze large datasets to map cellular diversity in entire organisms, examine cell types and states, cellular interactions and functions.

Nature Cell Biology is a Transformative Journal; authors can publish using the traditional publishing route OR via immediate gold Open Access.

Our Open Access option complies with funder and institutional requirements.


    • Specialized activities of ribosomal components that regulate the expression of specific genes is an emerging field of research. A new study identifies alternative splicing of a ribosomal protein between the peripheral and core regions of glioblastoma tumours to produce isoforms with distinct functions.

      • Naomi R. Genuth
      • Maria Barna
      News & Views
    • Cellular senescence induced by DNA replication and telomere attrition contributes to organ dysfunction, inflammation and impaired immunity. A study reveals that antigen-presenting cells provide telomeric DNA to CD4+ T cells in synaptic contact, which enables the suspension of senescence, T cell expansion and long-lived immunity.

      • Anna Carey
      • Laura Niedernhofer
      • Christina Camell
      News & Views
    • The Rag GTPases form the link between extracellular nutrients and the activation of mTORC1. RagA/B and RagC/D have been considered functionally redundant, but two studies now show that each isoform and gene have specific features, making their control of mTORC1 activity more nuanced and complex than previously appreciated.

      • Nicola Alesi
      • Elizabeth P. Henske
      News & Views
    • Aggregation of the RNA-binding protein TDP-43 is commonly observed in neurodegenerative disorders. A new study reveals that this process may be blocked by HSPB1, a small heat shock protein that can also regulate TDP-43 phase separation. This may be relevant to neurodegeneration, as loss of HSPB1 correlates with TDP-43 pathology.

      • Yuna M. Ayala
      • Zachary R. Grese
      News & Views
Metabolic circuits

Metabolic communication across biological scales

This Collection showcases recent articles from Nature Cell Biology, Nature Metabolism and Nature Reviews Molecular Cell Biology covering cellular to systemic metabolic regulation. This selection accompanies the Nature Conference “Metabolic Communication Across Biological Scales” and provides a resource about current trends and directions in this field.


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