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Volume 40 Issue 2, February 2022

A compact Cas13

Rendering of the predicted structure of an RNA editor based on the compact Cas13bt enzyme presented by Kannan et al. Cas13bt is small enough to be delivered using adeno-associated viruses, even when additional functional domains, such as deaminases, are fused to the enzyme.

See Kannan et al.

Image: Han Altae-Tran. Cover Design: Erin Dewalt.


  • Advances in technology and changes to healthcare during the pandemic may finally realize the vision of patient-centric blood testing espoused by disgraced Theranos CEO Elizabeth Holmes.



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News & Views

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Amendments & Corrections

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Careers & Recruitment

  • Career Feature

    • The complicated and labor-intensive manufacturing of novel cell and gene therapies requires efforts to improve workforce development programs for the nascent cell therapy industry broadly, and for cell manufacturing more specifically.

      • Linda D. Ho
      • Hadassah L. Robbins
      • Aaron D. Levine
      Career Feature
    • A quarterly snapshot of job expansions, reductions and availability in the biotech and pharma sectors.

      • Michael Francisco
      Career Feature
  • People

    • Recent moves of note in and around the biotech and pharma industries.

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