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Volume 38 Issue 6, June 2020

Cas13d guide design principles

Optimizing guide RNA design for Cas13. With data from massively parallel screens, Wessels et al. develop computational models to identify optimal guide RNAs for the RNA-targeting CRISPR enzyme Cas13d.

See Wessels et al.

Image: Christian Stolte. Cover Design: Erin Dewalt.


  • Insufficient SARS-CoV-2 testing has left many nations flying blind as they reopen their economies. Without adequate testing, new infections could outrun control measures.



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  • Patents

    • Recent patents related to vaccines and methods of treatment of coronaviruses.

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Amendments & Corrections

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Careers & Recruitment

  • Career Feature

    • Though academic institutions have contributed enormously to the remarkable growth in the healthcare industry, a key limiting resource for this continued growth is the creation of career opportunities for doctoral graduates.

      • Sinje Gehr
      • Craig C. Garner
      • Karin N. Kleinhans
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  • People

    • Recent moves of note in and around the biotech and pharma industries.

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