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Volume 37 Issue 7, July 2019

Volume 37 Issue 7

Clinical metagenomics on a nanopore

A scanning electron micrograph of phlegm in the trachea with bacteria shown in mauve. Charalampous et al. devise a metagenomics diagnostic method for bacterial lower respiratory tract infection that includes saponin-based host DNA depletion and nanopore long-read sequencing. Magnification: x1,500 when printed at 10cm wide.

See Charalampous et al.

Image: Steve Gschmeissner/ Science Photo Library (C038/6622). Cover Design: Erin Dewalt.

Editorial

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    Sky-high-priced gene therapies face slow uptake and market failure unless healthcare payers and drug makers can find common ground in ‘pay-for-performance’ reimbursement.

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    Public companies continued to ride the crest of the wave of financing, licensing deals and regulatory approvals, but clouds may be looming on the horizon for the biggest biotech players. Chris Morrison and Riku Lähteenmäki report.

    • Chris Morrison
    • Riku Lähteenmäki
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    Recent patents related to synthetic genes, microRNAs and nanoparticles.

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    A sample of goings-on in and around the biotech and pharmaceutical industry.

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