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Volume 37 Issue 5, May 2019

Volume 37 Issue 5

Engineered macrophages as diagnostics

A depiction of a cell-based sensor for cancer. Aalipour et al. engineer macrophages to express reporter proteins traceable in the blood when they activate the arginase-1 promoter.

See Aalipour et al.

Image: Jim Strommer, Stanford University. Cover Design: Erin Dewalt.


  • Editorial |

    Nature Biotechnology’s peer review trial with Code Ocean highlights the importance of ‘containers’ in enhancing software usability, reproducibility and code-writing in academia.




  • Feature |

    2018 was the year when the funding machine for privately held biotech companies went into overdrive, with mega-rounds and rapid flotations. John Hodgson brings us this deep dive.

    • John Hodgson
  • Patents

  • Patents |

    Recent patents related to metagenomic analysis for compound identification and sequence assembly.

News & Views

  • News & Views |

    In vivo studies indicate that cytosine but not adenine base editors induce elevated levels of genome-wide off-target substitutions.

    • Jia Chen
    • Bei Yang
    • Li Yang


Amendments & Corrections

Careers & Recruitment

    Career Feature

  • Career Feature |

    A quarterly snapshot of job expansions, reductions and availability in the biotech and pharma sectors.

    • Michael Francisco
  • People

  • People |

    A sample of goings-on in and around the biotech and pharmaceutical industry.


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