Volume 36 Issue 8, August 2018

Volume 36 Issue 8

An illustration of a tumor surrounded by T cells bearing cytokine 'backpacks'. The cytokine-delivery system developed by Tang et al. releases cytokines specifically at the tumor after T cells recognize a tumor antigen (p 707). Image credit: Yutao Dong

Editorial

  • Editorial |

    Despite spooking investors, new insights into DNA repair and the CRISPR gene-editing system are part and parcel of its progress from research tool to human therapy.

News

Opinion and Comment

Feature

News and Views

Research

    Articles

  • Article |

    Rapid, multiplex identification of pathogens and disease-associated mutations is possible with a new semiconductor biochip.

    • Arjang Hassibi
    • , Arun Manickam
    • , Rituraj Singh
    • , Sara Bolouki
    • , Ruma Sinha
    • , Kshama B Jirage
    • , Mark W McDermott
    • , Babak Hassibi
    • , Haris Vikalo
    • , Gelareh Mazarei
    • , Lei Pei
    • , Luc Bousse
    • , Mark Miller
    • , Mehrdad Heshami
    • , Michael P Savage
    • , Michael T Taylor
    • , Nader Gamini
    • , Nicholas Wood
    • , Pallavi Mantina
    • , Patrick Grogan
    • , Peter Kuimelis
    • , Piyush Savalia
    • , Scott Conradson
    • , Yuan Li
    • , Rich B Meyer
    • , Edmond Ku
    • , Jessica Ebert
    • , Benjamin A Pinsky
    • , Gregory Dolganov
    • , Tran Van
    • , Kirsten A Johnson
    • , Pejman Naraghi-Arani
    • , Robert G Kuimelis
    •  & Gary Schoolnik
  • Article |

    Systematic evaluation of library preparation methods for small RNA-seq identifies reproducible and accurate methods.

    • Maria D Giraldez
    • , Ryan M Spengler
    • , Alton Etheridge
    • , Paula M Godoy
    • , Andrea J Barczak
    • , Srimeenakshi Srinivasan
    • , Peter L De Hoff
    • , Kahraman Tanriverdi
    • , Amanda Courtright
    • , Shulin Lu
    • , Joseph Khoory
    • , Renee Rubio
    • , David Baxter
    • , Tom A P Driedonks
    • , Henk P J Buermans
    • , Esther N M Nolte-'t Hoen
    • , Hui Jiang
    • , Kai Wang
    • , Ionita Ghiran
    • , Yaoyu E Wang
    • , Kendall Van Keuren-Jensen
    • , Jane E Freedman
    • , Prescott G Woodruff
    • , Louise C Laurent
    • , David J Erle
    • , David J Galas
    •  & Muneesh Tewari
  • Letters

  • Letter |

    Therapeutic inhibition of the immunosuppressive IDO1–TDO pathway in tumors is achieved in vivo with an enzyme.

    • Todd A Triplett
    • , Kendra C Garrison
    • , Nicholas Marshall
    • , Moses Donkor
    • , John Blazeck
    • , Candice Lamb
    • , Ahlam Qerqez
    • , Joseph D Dekker
    • , Yuri Tanno
    • , Wei-Cheng Lu
    • , Christos S Karamitros
    • , Kyle Ford
    • , Bing Tan
    • , Xiaoyan M Zhang
    • , Karen McGovern
    • , Silvia Coma
    • , Yoichi Kumada
    • , Mena S Yamany
    • , Enrique Sentandreu
    • , George Fromm
    • , Stefano Tiziani
    • , Taylor H Schreiber
    • , Mark Manfredi
    • , Lauren I R Ehrlich
    • , Everett Stone
    •  & George Georgiou

Careers and Recruitment

Errata