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Mouse hippocampal neurons expressing membrane-anchored fluorescent proteins. Tillberg et al. (p 987) and Ku et al. (p 973) improve expansion microscopy approaches to enable super-resolution image quality with off-the-shelf reagents. Image credit: Fei Chen, Dawen Cai & Edward Boyden
A common method for determining the patent status of medicines internationally is highly imprecise and complicates medicine access by obscuring the true medicine patent landscape for policymakers and procurement officers.
Sources of error and bias in PCR amplification of microbial samples for 16S rRNA gene sequencing are systematically evaluated, and best-practice recommendations for reliable amplification are made.
Softening in tomatoes is uncoupled from ripening by silencing a pectate lyase, thereby identifying a route to engineering (or breeding) tomatoes with better shelf life and flavor.
Protease-free expansion of organ-size tissue enables multiplexed super-resolution imaging of protein organization from the tissue-wide scale down through the nanoscale.
Interdisciplinary studies come with high risk, but the prospects of both advancing science and pushing forward one's professional career make for high rewards.
