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Artist's impression of an experiment establishing the specificity patterns of the Cpf1 RNA-guided nuclease. Kim et al. (p 875) and Kleinstiver et al. (p 881) analyze the genome-wide on-target and off-target specificities of Cpf1 in vitro and in human cells. Image credit: IBS, Institute for Basic Science, Seoul, South Korea
A look at the global landscape of biofuel patenting shows that, after surging between 2004 and 2008, the invention of biofuel technologies slowed considerably, and in many countries went into decline. Global trends point to an uncertain future, in particular, for advanced biofuels.
GNPS is an open-access community-curated analysis platform for sharing natural product mass spectrometry data that enables continuous, automatic reanalysis of deposited 'living' data sets.
Analyzing and integrating a broad range of behavioral phenotypes enables prediction of underlying genetic mutations in mouse models of Huntington's disease.
Simultaneous imaging of neural activity in large regions of the mouse brain at subcellular resolution is made possible with a wide field-of-view two-photon microscope.
Canola oil containing healthful long chain omega-3 polyunsaturated fatty acids is produced from plants engineered with an algal polyketide synthase-like enzyme system.