Increasing public and private sector cooperation to support long-term, longitudinal population studies is critical to advance translational research on complex diseases.
Volume 31 Issue 3, March 2013
As industry, governments and academia increasingly rely on patent landscapes to map scientific and technological trends, an interdisciplinary workshop provides recommendations for developing consistent and transparent landscaping practices.
News & Views
The MuTect algorithm for calling somatic point mutations enables subclonal analysis of the whole-genome or whole-exome sequencing data being generated in large-scale cancer genomics projects.
The genome of human cells is edited using the bacterial RNA-guided Cas9 endonuclease.
A CRISPR-Cas system is harnessed to introduce template-driven mutations in S. pneumoniae and E. coli at high efficiency without requiring selectable markers.
A draft sequence of the staple crop kabuli chickpea, together with resequencing and analysis of 90 additional lines from 10 countries, provides a resource for breeders.
Proteins are denatured and threaded through a nanopore by a bacterial unfoldase, allowing certain features of the protein sequence to be detected.