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Volume 31 Issue 3, March 2013

Artistic rendition of DNA cleavage directed by the Cas9 endonuclease complexed with a synthetic single guide RNA. Three groups demonstrate site-specific genome modification in zebrafish embryos (p 227), human cells (p 230) and bacteria (p 233). Credit: Stephen Dixon

Volume 31 Issue 3

Editorial

  • Increasing public and private sector cooperation to support long-term, longitudinal population studies is critical to advance translational research on complex diseases.

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Data Page

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News Feature

  • Recent clinical success of antibody-drug conjugates is resparking interest in the technology for tackling unmet cancer needs. Sarah Webb investigates.

    • Sarah Webb
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Bioentrepreneur

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Correspondence

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Analysis

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Perspective

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Brief Communication

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Letter

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