Volume 31 Issue 2, February 2013

Volume 31 Issue 2

Cherry and currant tomatoes of varying ripeness. Zhong et al. use whole-genome cytosine methylation and transcription factor binding analyses to show that epigenome dynamics influence the developmental transition to ripening (p 154). Credit: Ryan McQuinn

Editorial

  • Editorial |

    Despite their limitations, in vitro assays are a simple means for assessing the drug sensitivity of a patient's cancer. After consulting experts in the community, we think such assays deserve a second look.

News

Bioentrepreneur

    Building a business

  • Bioentrepreneur |

    A survey of stakeholders in the Indian biotech sector reveals three major challenges that will need to be addressed to spark further entrepreneurial activity.

    • Gayatri Saberwal

Opinion and Comment

Feature

News and Views

Computational Biology

    Analysis

  • Analysis |

    The most comprehensive analysis to date of models of transcription-factor binding specificity reveals the best methods for predicting in vivo binding from in vitro data.

    • Matthew T Weirauch
    • , Atina Cote
    • , Raquel Norel
    • , Matti Annala
    • , Yue Zhao
    • , Todd R Riley
    • , Julio Saez-Rodriguez
    • , Thomas Cokelaer
    • , Anastasia Vedenko
    • , Shaheynoor Talukder
    • , DREAM5 Consortium
    • , Phaedra Agius
    • , Aaron Arvey
    • , Philipp Bucher
    • , Curtis G Callan Jr
    • , Cheng Wei Chang
    • , Chien-Yu Chen
    • , Yong-Syuan Chen
    • , Yu-Wei Chu
    • , Jan Grau
    • , Ivo Grosse
    • , Vidhya Jagannathan
    • , Jens Keilwagen
    • , Szymon M Kiełbasa
    • , Justin B Kinney
    • , Holger Klein
    • , Miron B Kursa
    • , Harri Lähdesmäki
    • , Kirsti Laurila
    • , Chengwei Lei
    • , Christina Leslie
    • , Chaim Linhart
    • , Anand Murugan
    • , Alena Myšičková
    • , William Stafford Noble
    • , Matti Nykter
    • , Yaron Orenstein
    • , Stefan Posch
    • , Jianhua Ruan
    • , Witold R Rudnicki
    • , Christoph D Schmid
    • , Ron Shamir
    • , Wing-Kin Sung
    • , Martin Vingron
    • , Zhizhuo Zhang
    • , Harmen J Bussemaker
    • , Quaid D Morris
    • , Martha L Bulyk
    • , Gustavo Stolovitzky
    •  & Timothy R Hughes

Research

Careers and Recruitment