Volume 22 Issue 5, May 2004

Volume 22 Issue 5

A root of a poplar colonized by the green fluorescent protein-labeled endophytic bacterium Pseudomonas putida VM1453. Photo courtesy of Kieran Germaine, David Ryan and David Dowling Department of Applied Biology & Chemistry, Institute of Technology, Carlow, Ireland). On page 583, van der Lelie and colleagues describe a yellow lupin containing a modified endophytic symbiont capable of toluene degradation.



Opinion and Comment


  • Feature |

    Has structural bioinformatics advanced enough to form the core of a drug discovery program? A new generation of companies exploiting structure-focused technologies is counting on it.

    • Karl A Thiel

News and Views

  • News & Views |

    Ankyrin repeats generate high-affinity protein binders with biophysical properties that may favor therapeutic applications.

    • Ian M Tomlinson
  • News & Views |

    Chemical screening in a zebrafish mutant has turned up two compounds that rescue a heart defect, but will this yield new drugs?

    • Jonathan Margolis
    •  & Greg D Plowman
  • News & Views |

    The genome sequence of Thermus thermophilus may provide new insights into heat-tolerant enzymes and metabolic pathways of biotechnological potential.

    • Wolfgang Liebl
  • News & Views |

    Genetically modified (GM) bacteria improve the degradation of toluene in plants.

    • Bernard R Glick
  • News and Views Feature

  • News and Views Feature |

    The complete genome sequence of the rat provides new signposts on the road to functional determination in higher eukaryotes.

    • Ismail Kola



Computational Biology

Computational Biology