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Isolated hair follicle stem cells form all components of the cutaneous epithelium, including new hair follicles, hairs, epidermis and sebaceous glands, when injected together with mesenchymal cells into immunodeficient mice. The hair follicle stem cells were isolated from Rosa reporter mice expressing lacZ in every cell (Morris et al., p 411).
Probes that reversibly recognize oligohistidine sequences engineered into proteins can provide insights into the structure and location of proteins in living cells.