Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Antibacterials for any target

RNA-guided nucleases provide a strategy for killing specific bacterial species in complex populations.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Directed cleavage and loss of targeted DNA.

Marina Corral Spence/Nature Publishing Group

References

  1. Citorik, R., Mimee, M. & Lu, T. Nat. Biotechnol. 32, 1141–1145 (2014).

    Article  CAS  Google Scholar 

  2. Bikard, D. et al. Nat. Biotechnol. 32, 1146–1150 (2014).

    Article  CAS  Google Scholar 

  3. Jinek, M. et al. Science 337, 816–821 (2012).

    Article  CAS  Google Scholar 

  4. Gomaa, A.A. et al. MBio 5, e00928-13.

  5. Silver, L.L. Clin. Microbiol. Rev. 24, 71–109 (2011).

    Article  CAS  Google Scholar 

  6. The Pew Charitable Trusts. Antibiotics Currently in Clinical Development http://www.pewtrusts.org/en/multimedia/data-visualizations/2014/antibiotics-currently-in-clinical-development (2014).

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Lynn L Silver.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Silver, L. Antibacterials for any target. Nat Biotechnol 32, 1102–1104 (2014). https://doi.org/10.1038/nbt.3060

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nbt.3060

This article is cited by

Search

Quick links

Nature Briefing Microbiology

Sign up for the Nature Briefing: Microbiology newsletter — what matters in microbiology research, free to your inbox weekly.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing: Microbiology