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Medicines from microbiota

Nature Biotechnology volume 31, pages 309–315 (2013)Cite this article

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Five years after the launch of the Human Microbiome Project, several ventures are seeking to capitalize on the clinical promise of microbiome modulation. Commercialization of drugs that influence the human flora poses some unique scientific, translational and regulatory challenges.

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Figure 1: Journal articles and INPADOC (International Patent Documentation Center) families, including patent and patent applications referencing the terms microbiome, microbiota, gut flora, or gut microflora.
Figure 2: Broadening interest in the microbiome.
Figure 3: Spectrum of microbiome-derived modulators being pursued by biotech companies, ranging from ecosystem-level interventions to single-target approaches.

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Authors and Affiliations

  1. Bernat Olle is a principal at PureTech Ventures in Boston, and co-founder and COO of Vedanta Biosciences, also in Boston, Massachusetts, USA.,

    Bernat Olle

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  1. Bernat Olle
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Correspondence to Bernat Olle.

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Competing interests

O.B. is an employee of PureTech Ventures, a company that owns an interest in Vedanta Biosciences, and owns shares of PureTech Ventures and Vedanta Biosciences.

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Olle, B. Medicines from microbiota. Nat Biotechnol 31, 309–315 (2013). https://doi.org/10.1038/nbt.2548

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