Collections

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    This collection includes recent articles from across the Nature group of journals and showcases both the latest advances in the methodologies used to study genome organization, and our recent understanding of how genome organization and nuclear architecture regulate gene expression, cell fate and cell function in physiology and disease.

    Image: V. Summersby
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    Image: Erin Dewalt, Lauren Robinson, David Schilter, Rachael Tremlett
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    Stem cells are well on their way into the clinic and can be used in a variety of applications, such as disease modelling, drug screening and for regenerative medicine. This collection showcases research articles, reviews and protocols from across the Nature journals to highlight the striking advances made in basic and translational stem cell research.

    Image: Miguel Quiros and Asma Nusrat
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    Popularization of super-resolution imaging techniques has allowed cell biologists to probe cell structure and function in previously unattainable detail. These methodologies continue to evolve, with new improvements that allow tailoring the available techniques to a particular need and application. This collection showcases primary research articles, reviews and protocols and highlights these recent developments by exemplifying the new, interesting applications of super-resolution microscopy as well as related tool development.

    Image: Bertocchi et al., Nature Cell Biology volume 19, pages 28–37 (2017).
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    Image: Digital background: Jakarin2521/ iStock / Getty Images Plus
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    A collection of research and data papers published across Nature Research, from the fifth cycle of the Functional ANnoTation Of the Mammalian genome project (FANTOM).

    Image: Richard Janissen - TU Delft
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    In this collection, the cancer editorial community of the Nature journals presents the most recently published articles on cancer evolution. The topic is discussed from different angles (preclinical, translational and clinical), and across a range of tumour types.

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    A joint focus with Nature Reviews Drug Discovery on RNA-based therapeutics presents a series of articles detailing recent progress in chemistries and delivery technologies that have propelled the clinical advancement of oligonucleotide therapies as well as highlighting commercial advances in RNA vaccines.

    Image: Nature Publishing Group
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    Single cell technologies are becoming increasingly important tools in biological analysis. Complementing average measurements on bulk populations of cells, single-cell measurements provide a finer-grained picture of complex biology and unmask heterogeneity that is present in tissues.

    Image: Jezperklauzen
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    Advances in technology across all areas of science have ushered in an era of big data, providing researchers with unprecedented opportunities to understand how biological systems function and interact. Scientists are now faced with the challenge of developing sophisticated computational tools capable of unravelling these data and uncovering important biological signals. Computational biology will continue to play a key role in facilitating multi-disciplinary collaborations, encouraging data sharing and establishing experimental and analytical standards in the life sciences.

    Image: Sam Rios
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    Nature Biotechnology is 20! We have brought together a collection of Features celebrating two decades of the science and business of biotech, with an eye on the future.

    Image: VLADGRIN / Sam Rios