Commentary

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  • The Open Material Transfer Agreement is a material-transfer agreement that enables broader sharing and use of biological materials by biotechnology practitioners working within the practical realities of technology transfer.

    • Linda Kahl
    • Jennifer Molloy
    • Drew Endy
    CommentaryOpen Access
  • Greater safeguards are needed to address the personal safety, security and privacy risks arising from increasing adoption of neurotechnology in the consumer realm.

    • Marcello Ienca
    • Pim Haselager
    • Ezekiel J Emanuel
    Commentary
  • Expert curation at present remains the only reliable solution for interpretation of mutation information in the clinical practice of oncology.

    • Kathryn D Bungartz
    • Kristen Lalowski
    • Sheryl K Elkin
    Commentary
  • Why digitally powered real-world evidence is the fix needed for our broken clinical trials system.

    • Vicki Seyfert-Margolis
    Commentary
  • Magistral drug preparation offers a model to circumvent many of the technological, regulatory and financial challenges that prevent provision of the right drug at the right time to the right patient.

    • Huub Schellekens
    • Mohammed Aldosari
    • Enrico Mastrobattista
    Commentary
  • To ensure global food security for all, the adoption of crop improvement technologies is no longer just an option—it is an imperative.

    • Richard B Flavell
    Commentary
  • Changing the academic reward system to improve translational medicine should start by moving away from a myopic focus on publications.

    • Gerard Pasterkamp
    • Imo Hoefer
    • Berent Prakken
    Commentary
  • Lessons from the US Biodefense program should inform international efforts to build a medical countermeasure enterprise for emerging infectious diseases.

    • Kendall Hoyt
    • Richard Hatchett
    Commentary
  • To upend current barriers to sharing clinical data and insights, we need a framework that not only accounts for choices made by trial participants but also qualifies researchers wishing to access and analyze the data.

    • John Wilbanks
    • Stephen H Friend
    CommentaryOpen Access
  • Digital medicine offers the possibility of continuous monitoring, behavior modification and personalized interventions at low cost, potentially easing the burden of chronic disease in cost-constrained healthcare systems.

    • Joseph C Kvedar
    • Alexander L Fogel
    • Daphne Zohar
    Commentary
  • The markets may be softening on biotech, but overall the sector remains in an incredibly strong environment.

    • Bruce L Booth
    Commentary
  • For the benefits of digital medicine to be fully realized, we need not only to find a shared home for personal health data but also to give individuals the right to own them.

    • Leonard J Kish
    • Eric J Topol
    Commentary
  • Digital medicine companies can incorporate and build on existing business models in tech and biomedicine to bring transformational new products to market and eventually reshape medicine.

    • David Steinberg
    • Geoffrey Horwitz
    • Daphne Zohar
    Commentary
  • New instruments are needed to realize the potential of quantitative and systematic imaging of living samples. But what would such a microscope look like?

    • Nico Scherf
    • Jan Huisken
    Commentary
  • Clear and logical regulatory guidelines on the process and requirements for approval of health apps and wearable sensors will be essential for the digital medicine sector to unleash its full potential.

    • Eric Elenko
    • Austin Speier
    • Daphne Zohar
    Commentary
  • One of molecular biology's intellectual leaders, Alex Rich made fundamental discoveries concerning nucleic acids and ribosomes, which served not only as a foundation for modern biology but also spurred the field of biotechnology.

    • Shuguang Zhang
    • Burghardt Wittig
    Commentary
  • In the coming years, patient phenotypes captured to enhance health and wellness will extend to human interactions with digital technology.

    • Sachin H Jain
    • Brian W Powers
    • John S Brownstein
    Commentary
  • Healthcare priorities all too often ignore the importance of diagnostics for disease control and case management. The Ebola epidemic illustrates the folly of this attitude when few therapeutic or prophylactic interventions are available.

    • Mark D Perkins
    • Mark Kessel
    Commentary