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  • VitaDAO funds longevity research through a blockchain-based decentralized autonomous organization (DAO), showcasing the potential of collaborative, transparent and alternative systems while also highlighting the challenges of coordination, regulation, biases and skepticism in reshaping traditional research financing methods.

    • Simone Fantaccini
    • Laura Grassi
    • Andrea Rampoldi
    Comment
  • Biotechnology (biotech) clusters have evolved over time. Being a top biotech region in the early years 1978–1990 still positively correlates with the cluster’s biotech strength decades later. An entrepreneurial orientation of scientific actors as well as a variety of networks with partners outside the cluster both contribute to sustained biotech activity.

    • Bart Van Looy
    • Grabowska Marcelina
    • Koenraad Debackere
    Comment
  • Pfizer created a ‘light-speed’ approach to meet the challenge of vaccinating the world against COVID-19. It involved developing new strategies for all aspects of vaccine development, from sourcing materials and scaling up manufacturing to transportation and dosing.

    • Nicholas Warne
    • Margaret Ruesch
    • Mikael Dolsten
    Comment
  • The MicroArray Quality Control consortium—a 16-year international effort led by the FDA and involving hundreds of scientists from academia, industry and government—helped make genomic medicine a reality.

    • Marc Salit
    • Janet Woodcock
    Comment
  • The not-for profit foundation n-Lorem seeks to provide experimental antisense oligonucleotide treatments to patients with ultra-rare disease free for their entire lifetime.

    • Stanley T. Crooke
    Comment
  • Can traditional computational analysis and machine learning help compensate for inadequate peer review of drug-repurposing papers in the context of an infodemic?

    • Jeremy M. Levin
    • Tudor I. Oprea
    • Alex Zhavoronkov
    Comment
  • The stepwise application of biotechnology will be instrumental to addressing four key challenges of Martian settlement.

    • Shannon N. Nangle
    • Mikhail Y. Wolfson
    • Marika Ziesack
    Comment
  • To take full advantage of deep-learning solutions in healthcare, the United States and China should collaborate, not compete.

    • Eric Topol
    • Kai-Fu Lee
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