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The Tibetan glacier genome and gene catalog includes 3,241 metagenome-assembled or cultured genomes spanning 30 phyla and over 25 million genes encoding non-redundant proteins. This catalog provides a wealth of resources for archiving glacier microbial diversity and bioprospecting for bioactive compounds, as well as a platform for global comparison of glacier microbiomes.
After decades of research and development, devices for detecting infectious agents in breath are finally maturing, with SARS-CoV-2 galvanizing progress. Carrie Arnold reports.
Most plant hormone sensors, including the abscisic acid receptor PYR1, function through chemically induced dimerization. Using computationally designed libraries of PYR1, we created high-affinity receptors for 21 structurally diverse ligands, setting the stage for large-scale small-molecule biosensor development
We developed two quantitative PCR-based assays to detect SARS-CoV-2-specific T cell immunity: qTACT and dqTACT. The assays quantify CXCL10 mRNA, after incubation of whole blood with viral peptides, as a proxy of an antigen-specific T cell response, and will allow population-level monitoring of cellular immunity to SARS-CoV-2.
