Browse Articles

Limitations of Alphafold2 structure prediction are addressed by including experimentally determined distance constraints.

Modeling contamination sources over multiple samples enhances the analysis of microbiome data.

Recent patents relating to methods, systems and toolkits related to synthetic biology.

Early-stage researchers can greatly benefit from education and skills development in venture creation and commercialization of discoveries.

Recent moves of note in and around the biotech and pharma industries.

Drug patents are different. To improve their quality ex ante, regulators can use predictive models.

Leveraging advances in hardware and probes, we have combined innovations in optics and algorithms to allow automated single-molecule-based super-resolution imaging at unprecedented throughput. This approach allows us to obtain nanoscale information from large cell populations, bridging the gap between imaging and indirect ensemble methods.

A single-cell screening approach identifies targets for CAR-T cells in acute myeloid leukemia.

A fast data processing platform enables super-resolution microscopy with increased throughput.

Fine-tuning gene expression is crucial for generating quantitative phenotypic changes and crop improvement. Using CRISPR–Cas base editing and prime editing, we engineered upstream open reading frames — eukaryotic translational control elements — in rice to incrementally downregulate translation to predictable and desired levels.

Plant traits are fine-tuned by stepwise downregulation of gene expression.