A model of 2′-O-hexadecyl (C16)-conjugated siRNA (orange) in complex with RISC (white) and mRNA (green). Brown et al. show that C16-conjugated siRNA achieves efficient, durable targeted gene silencing in the central nervous system, eye and lung.

Protein structure prediction

RGN2 predicts a protein’s structure from its sequence without a multiple sequence alignment

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