The detection of mobile genetic elements is crucial for exploring the ecology and evolution of microbial communities, and it has diverse implications in biotechnology and public health. geNomad is a computational framework that enables researchers to precisely identifiy and annotate plasmids and viruses in sequencing data on a large scale.

Pfeiffer and Stafforst review and discuss the state-of-the-art tools for precision editing of RNA bases.

By using fixed charges to engineer a strong electroosmotic flow, we achieve the unidirectional transport of natural polypeptides across nanopores. Our approach enables native proteins to be transported enzymatically and non-enzymatically in the absence of denaturant and electrophoretic tags, with potential applications for protein sequencing.

BugSigDB is a community-editable wiki that harmonizes how key microbial differential abundance methods and results are reported, identifying rare and common patterns across the literature of published host-associated microbiome studies.