Head of Receptor and Enzyme Section– Department of Molecular Screening and Pharmacology

Head of Receptor and Enzyme Section– Department of Molecular Screening and Pharmacology

H. Lundbeck A/S

Valby, Denmark

We are looking for a highly-motivated Section Head for our Receptor and Enzyme section. The Department of Molecular Screening and Pharmacology is divided into two sections; an Ion Channel section and a Receptor/Enzyme section. Our department is responsible for the molecular and cellular pharmacology input to Lundbeck’s drug discovery projects as well as our Development Projects. We use a broad range of in vitro enzyme activity, cell-based, radioligand binding, and electrophysiological assays. All assays are executed on state of the art technology platforms of various end-point and kinetic microplate readers, manual and automated electrophysiological platforms, and a range of tip-based or acoustic liquid handlers. The department resides in the division of Molecular Discovery and Innovation and plays a central role in the Research organization. The department of Molecular Screening and Pharmacology is fully integrated and fundamental to the identification, progression and optimization of novel drugs. We collaborate extensively with our colleagues from Medicinal Chemistry to enable structure-activity relationship in our projects and with our colleagues from our biology units to develop assays reflecting the molecular mechanism suitable for drug interaction. It is fundamental to our strategy that the molecular mechanism of action of novel therapeutics is captured in pharmacological relevant in-vitro assays.

Your job and key responsibilities
You will lead and manage our receptor/enzyme section of 4 scientist and 3 technicians to achieve results through a high-performance culture. You will, in close collaboration with Head of Ion Channel Section and Head of Department, be responsible for continuously improving and implementing our strategy to support hit identification and lead optimisation in our Drug Discovery projects. You will in this context also be responsible for implementation of new technologies as appropriate. You will make sure that the data generated in the section is of high quality and compliant with requirement for filling of drugs. You will, in collaboration with team members, manage our external CRO work and be responsible for the quality of data delivered. In addition to your leadership responsibilities, you will act as Molecular Screening representative in project(s), accountable for planning, conducting, and evaluating experiments and reporting these to the respective project teams. You will interact closely with head of departments from biology, chemistry, and research IT to ensure that molecular pharmacology aspects in the projects are handled in a diligent and competent manner.

We offer
The opportunity to lead a team of highly qualified colleagues working in an open atmosphere with excellent possibilities for scientific and personal development as well as further developing your leadership skills. Working in a company dedicated to discovering new medicines for people suffering from CNS diseases, such as psychiatric and neurological disorders.

Qualifications
Our preferred candidate has the following personal and professional qualifications:

Solid leadership experience
PhD degree in a relevant discipline, preferably molecular pharmacology and a documented understanding of in vitro molecular pharmacology
+2 years of post-doc experience
+3 years of experience within the Pharmaceutical industry and the Drug Discovery process.
Hands-on experience and publication in the field of molecular & cellular pharmacology
Experience with a broad range of target classes and modalities (inhibitors, agonists, PAM/NAM….)
Extensive external network to academia, other research facilities, and a proven track record of externally oriented activities.
Experience with planning and execution of MTS/HTS campaigns.
Fluency in English is essential both oral and written.

Further information
Please contact Senior Director of Molecular Design & Enabling Technologies Lena Tagmose LETA@lundbeck.com. Your application and CV should not be sent via email but using the link below. We also recommend that you have a look at our website. We will be conducting interviews as we receive applications.

Your application
Applications must be received no later than May 5th, 2019 and should include a cover letter with curriculum vitae as well as the names and contact details for two references

Please apply via recruiter’s website.

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