Senior Investigator, Human Genetics


Upper Providence, PA, United States

We are seeking a motivated, innovative, skilled and enthusiastic geneticist to join our expanding team within the Human Genetics department. Candidates should be keen to apply state of the art genetic knowledge to drive decision making across the GSK pipeline, working in partnership with scientists in HG and in the broader Research organisation, to generate biological insights that will translate into innovative new medicines for patients.

At the core of GSK’s R&D approach is the identification of new medicines by leveraging the vast amounts of human genetic and genomic data now being generated and applying cutting edge technologies in functional genomics and machine learning.

Within the Human Genetics team, we leverage major scientific and technological advances, including investment in biobanks linked to large-scale human health databases, cutting-edge informatics platforms and integration of biological pathway and functional genomics data to identify novel targets. We continue to evaluate these targets throughout their life in the pipeline, using genetics and genomics to identify the patients that are most likely to benefit and biomarkers to select these patients and assess efficacy.

The successful candidates will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and external collaborators to advance GSK drug discovery and clinical development. This field-leading research addresses important drug discovery and development challenges, directly impacts GSK’s R&D pipeline, and leads to publication in top scientific journals.

Selected candidates will:

identify of opportunities for genetics based science to improve GSK target quality and use human genetic evidence to drive decisions on target selection, validation and patient stratification.
Participate in project teams with GSK scientists and external collaborators. Be responsible for effective communication of genetic findings, with expert interpretation, to relevant stakeholdes and project teams.
Find creative solutions and work with agility to address challenging scientific questions.
Contribute to the developing science of drug target identification and validation, providing scientific expertise within Human Genetics and across the Research organization.

Why you?
Basic Qualifications:
We are looking for professionals with these required skills to achieve our goals:

M.A., M.S., Ph.D, or equivalent experience in human genetics, statistical genetics, pharmacogenetics, genomics, clinical pharmacology, biology or related field.
Demonstrated ability to drive genetics based scientific projects
Demonstrated skills working in teams to find creative ways to address scientific questions.
Strong verbal and written communication skills

Preferred Qualifications:
If you have the following characteristics, it would be a plus:

Data science skills to collect, integrate, mine and analyze complex biological data and translate them into testable hypotheses.
Knowledge of functional genomics, immunology or epidemiology
Experience leveraging external collaborations to augment internal capabilities.
Integration of of additional molecular data, eg from gene expression profiling, metabolomics, or proteomics, into genetic analyses.

Why GSK?
Our values and expectations are at the heart of everything we do and form an important part of our culture.

These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities:

Agile and distributed decision-making – using evidence and applying judgement to balance pace, rigour and risk.
Managing individual and team performance.
Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution.
Implementing change initiatives and leading change.
Sustaining energy and well-being, building resilience in teams.
Continuously looking for opportunities to learn, build skills and share learning both internally and externally.
Developing people and building a talent pipeline.
Translating strategy into action – a compelling narrative, motivating others, setting objectives and delegation.
Building strong relationships and collaboration, managing trusted stakeholder relationships internally and externally.
Budgeting and forecasting, commercial and financial acumen.

Please apply via recruiter’s website.

Quote Reference: 204538