Postdoctoral Research Scientist
Fixed-term, 3 years
£35,859 – £38,700 pa inclusive*
We are looking to recruit enthusiastic, curious and highly-motivated scientists for a 3-year postdoctoral position at the MRC London Institute of Medical Sciences (LMS), to join the Chromatin & Development group, headed by Dr Michelle Percharde. The LMS is a leading MRC-funded Institute affiliated with Imperial College London, based on the Hammersmith Hospital Campus in West London. The LMS provides a thriving research environment, state-of-the-art facilities, and the opportunity to pursue innovative, multi-disciplinary projects. Visit: http://www.lms.mrc.ac.uk
The Chromatin & Development group is a recently-established team focused on understanding the molecular events surrounding cell fate choices during early development. Our recent research indicates that Transposable Elements (TEs) have important, undiscovered roles during development, and projects in the lab include uncovering how TE regulation is important during embryogenesis. We are furthermore investigating how unrestrained TE expression may contribute to cases of disease. To answer these questions, we routinely use mouse and human embryonic stem cells (ESCs) and mouse embryos as models, adopting a combination of genome-wide techniques, CRISPR/Cas9 technology, high-resolution microscopy, biochemistry and molecular embryology approaches to probe gene and TE function. Visit www.perchardelab.com and https://lms.mrc.ac.uk/research-group/chromatin-and-development/ for more information.
Successful candidates must have the following essential attributes:
• PhD degree or equivalent experience in a relevant biological/biomedical discipline (or be in the final stages of completing one)
• One or more first-author publications in a peer-reviewed internationally recognized journal (being submitted or published)
• Strong background in epigenetics, developmental biology and/or gene regulation
• Significant research experience working with mammalian biological systems (e.g. mammalian tissue culture, ESCs, mouse models)
• Extensive practical experience in biochemical and molecular biology techniques (e.g. ChIP, qRT-PCR, western blotting, cloning)
Please contact Dr Michelle Percharde with any informal enquiries (m.percharde at lms.mrc.ac.uk)
This is an MRC Postdoctoral Scientist position providing training and development supporting post-doctoral scientists in early or changed career paths helping establish them as successful research scientists in their chosen field.
The MRC London Institute of Medical Sciences is a research institute within UK Research and Innovation. UK Research and Innovation is a new entity that brings together nine partners to create an independent organisation with a strong voice for research and innovation, more information can be found at www.ukri.org
For full details of this post and to complete an online application, visit: https://mrc.tal.net/vx/lang-en-GB/appcentre-1/candidate/postings/1195 and upload your CV, the names and contacts of two scientific references, along with a cover letter stating why you are applying for this post (providing evidence against the requirements as per the Job Description and Person Specification). Please quote reference number LMS – 1071
Please note: interviews will be held between 3 – 5 June.
Closing date: 16 May 2019
*Salary quoted is inclusive of London weighting. Additional allowances comprise a £1,000 lump sum Settlement Allowance plus a yearly Training Allowance of £850 in the first year, paid in monthly instalments. The Training Allowance increases to £1,300 in year two, and £1,800 in the third year.