Postdoc position in the Hansen group at BRIC, Faculty of Health and Medical Sciences

Postdoc position in the Hansen group at BRIC, Faculty of Health and Medical Sciences

University of Copenhagen (UCPH)

Copenhagen, Denmark

Postdoc position in the Hansen group at BRIC, Faculty of Health and Medical Sciences, University of Copenhagen

We are looking for a highly motivated postdoc to join our group working on epigenetics and transcription in stem cell biology and disease.

The Hansen Group
Our group focuses on disease causing gene mutations linked to transcriptional regulation, and has a key interest is neurological diseases and cancer. We use state-of-the-art technologies such as CRISPR genome editing, chromatin immunoprecipitation followed by DNA sequencing (ChIP-seq), RNA-sequencing (RNA-seq) and a range of biochemical approaches such as protein complex purification and characterization by quantitative mass spectrometry, and activity assays.

The research projects
Our research currently covers two main projects: Project 1 focuses on the Activity-Dependent Neuroprotective Protein (ADNP), a transcription factor recently found to be mutated in children affected in the autism spectrum disorder named Helsmoortel Van der Aa syndrome (Helsmoortel et al., 2014(1)). Project 2 focuses on the transcription factor KLF4, known as one of the iPSC reprogramming factors (Takahashi and Yamanaka, 2006(2)), and its involvement in tumorigenesis (meningiomas). The projects involve cell culture models employing mouse embryonic stem cells as well a clinical material from patients (project 2).

1. Nat Genet. 2014 Apr; 46(4):380-4.
2. Cell. 2006 Aug 25; 126(4):663-76.

Your job
Your tasks would be to further develop the two projects by taking active part in the experimental design and practical execution, establishment of cell lines (CRISPR mediated genome editing) and biological assays, and bring the results to a stage of publication. We strive for team work and strong collaborations with groups within our institute and the clinical departments (Rigshospitalet and Odense University hospital), as well as international collaborators.

Qualifications
We expect you to be a highly motivated scientist with the following qualifications:

A PhD in Life Sciences or equivalent. Practical experience in molecular biology Practical experience with ChIP-seq and RNA-seq would be an advantage Excellent communication skills in English, written and spoken Proficient communication skills and ability to work in teams

Place of employment
The employment will be at BRIC (Biotech Research and Innovation Centre), Faculty of Health and Medical Sciences, University of Copenhagen. BRIC is located at the Biocenter, 10 min from the center of Copenhagen. We offer creative and stimulating working conditions in a dynamic and international research environment. Our research facilities include modern laboratories and a number of core facilities shared between the 26 research groups at BRIC. We have weekly seminars with invited speakers and internal seminars, as well as a young researchers club ASAP, a PhD students program (MoMeD) and a Postdoc Career Program. BRIC actively participates in the European alliance, EU-life, consisting of 13 excellent European life science research institutions.

Terms of salary and employment
The employment as postdoc is a fixed-term position, initially for 2 years with a possibility for extension. Starting 1’st of September 2019 or soon after according to agreement.
Salary, pension and terms of employment will be in accordance with the agreement between the Ministry of Finance and The Academics Central organization. Currently, the monthly salary starts at 34,079 DKK corresponding to app. 4,564 € plus an employer paid pension contribution (17.1%). Depending on qualifications a higher salary may be negotiated.

Non-Danish and Danish applicants may be eligible for tax reductions, if they hold a PhD degree and have not lived in Denmark in the last 10 years.

The position is covered by the “Memorandum of Job Structure for Academic Staff at the Universities” of September 18, 2015.

For further information please contact Associate Professor Klaus Hansen by e-mail: klaus.hansen@bric.ku.dk . Additional information regarding the group can be found at our home page at https://www.BRIC.ku.dk.

Foreign applicants may find the following link useful: www.ism.ku.dk (International Staff Mobility).

Application procedure
Please submit your application electronically by clicking “Apply now” below or via BRICs website on http://www.bric.ku.dk/jobs/.
The application must include the following documents/attachments- all in PDF format:
A. Motivation letter for your application (max one page).
B. Curriculum vitae (CV) containing information regarding education, work/research experience, language skills and other relevant information relevant for the position.
C. A certified and signed copy of 1) PhD certificate, and 2) Master of Science certificate. If the PhD has not yet been completed, a written statement from the main supervisor will be sufficient.
D. List of peer reviewed publications.
E. Names and contact information for two professional references.

Application deadline: May 15, 2019, 23.59 CET.

We reserve the right not to consider material received after the deadline, and not to consider applications or letters of recommendation that do not fulfill the above, mentioned requirements.

The further process
After the expiry of the deadline for applications, the authorized recruitment manager selects applicants for assessment on the advice of the hiring committee. All applicants are immediately notified whether their application has been passed for assessment by the unbiased assessor. On the assessment work has been completed each applicant has the opportunity to comment on the part of the assessment that relates to the applicant her/himself.

You can find more details regarding the recruitment process at http://employment.ku.dk/faculty/recruitment-process/.

The applicants will be assessed according to the Ministerial Order no. 242 of March 2012 on the Appointment of Academic Staff at Universities.

BRIC and the University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.

Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation – with good working conditions and a collaborative work culture – creates the ideal framework for a successful academic career.

Please apply via recruiter’s website.

Quote Reference: 149364

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