Research Technician - Mouse Colony Management

Research Technician - Mouse Colony Management

Howard Hughes Medical Institute (HHMI)

Dallas, TX, United States

Job Description

Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world. Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S.

The Howard Hughes Medical Institute has an opportunity for a Research Technician to join the laboratory of Dr. Sean Morrison, Investigator and Director of the Children’s Research Institute at UT Southwestern.  Dr. Morrison’s lab studies the mechanisms that maintain stem cell function in adult tissues and the ways in which cancer cells hijack these mechanisms to enable neoplastic proliferation.  A better understanding of these mechanisms offers the potential to yield new regenerative medicine and cancer therapies.  More information about Dr. Morrison’s lab can be found at:


We are seeking a highly-organized, methodical and reliable individual to manage the mouse colony in a large, fast-paced laboratory.  The Research Technician will be responsible for regulatory compliance, management of a large breeding colony, and oversight of mouse use in the laboratory.  This role is an excellent opportunity for a self-starter who wants the challenge of managing a large and diverse mouse population, serving a lab of approximately 30 individuals.  The colony contains over 100 strains of mice and would require the oversight of approximately 5,000 mice. 


Principal Responsibilities:


  • Manage a complex mouse breeding colony that involves many genetic backgrounds
  • Perform genotyping of genetically modified mice
  • Supervise other laboratory staff
  • Interact effectively with lab members and veterinary staff to ensure a high standard of care, organization, and regulatory compliance.
  • Communicate directly with Investigator, Researchers, Postdocs, and other lab staff regarding the status of mouse colony operations in an efficient and effective manner
  • Keep detailed records



Required Qualifications:

  • Bachelor’s degree in some area of biology or biomedicine
  • Experience managing a mouse breeding colony
  • Experience genotyping mice
  • Experience managing regulatory processes related to the use of rodents in research
  • Ability and motivation to perform careful, conscientious, and highly organized work
  • Excellent time management skills
  • Exemplary organizational skills



HHMI is an EOE.

Required Skills

Required Experience

Please apply via recruiter’s website.

Quote Reference: Howard Hughes Medical Institute (HHMI)-hhmi-986-908