Bioinformatician in Molecular Mechanisms of Lipid Traffic at Membrane Contact Sites

Department of Biochemistry, University of Oxford

Oxford, South East England, United Kingdom

Salary: Grade 7: £32,236 - £39,609 p.a.

We are seeking to appoint a Bioinformatician in the newly-established Kornmann Group. The Kornmann group studies the molecular mechanisms of lipid exchange at membrane contact sites, using a combination of yeast genomics screening and lipidomic profiling. This post is tasked with the following responsibilities: apply machine-learning algorithms to available genomics data generated using our Saturated transposon Analysis in Yeast (SATAY) protocol, to identify genes working in similar, redundant or parallel pathways for intracellular lipid traffic (see Michel et al. 2017); infer lipid exchange fluxes from lipidomics data, and metabolic labelling experiments, using fluxomics approaches; streamline the analysis of yeast genomic screens (see Michel et al. 2017), in order to allow facilitated analysis to the community of users and; develop analysis pipelines for the quantification of defined lipid species in complex samples.

You should hold a PhD/DPhil, or be near completion of a PhD/DPhil in a relevant subject area, and have relevant experience and knowledge in data analysis and computational biology using programming languages such as R, Matlab or python. You will have the ability to manage your own academic research and associated activities and have previous experience of contributing to publications and presentations. You must be able to work in a team to make new discoveries, present them in various setups, and drive them to publication. Knowledge or experience in mass spectrometry and/or yeast genomics-related data analysis would be beneficial.

This full-time fixed-term post is funded by the Wellcome Trust for up to 3 years in the first instance and is based at the Department of Biochemistry, South Parks Road, Oxford.

The actual starting salary offered will be based on qualifications and relevant skills acquired and will also be determined by the funding available.

To apply for this role and for further details including the job description and selection criteria, please see the document below. You will be required to upload a supporting statement and CV as part of your application.

The closing date for applications is 12.00 noon on Wednesday 1 May 2019, with interviews for shortlisted candidates to be held as soon as possible thereafter.

Please apply via recruiter’s website.

Quote Reference: University of Oxford-itox_ac-139933