Lead Scientist - Cell Phenotyping

Lead Scientist - Cell Phenotyping

Victor Chang Cardiac Research Institute

Sydney, Australia

  • Help the 3.7 million Australians affected by cardiovascular disease
  • World class research institute
  • Inner city location, close to public transport

About you
Are you an accomplished scientist with a passion for working with new technology? Are you looking to advance your career in academic research but prefer the lab bench to the office desk? Do you want to be part of a team undertaking cutting-edge cardiovascular research with innovative technology?

About us
The Victor Chang Cardiac Research Institute is dedicated to finding cures for cardiovascular disease and is one of the most respected heart research facilities in the world.

The Victor Chang Innovation Centre, supported by the leading cardiovascular research scientists in NSW and funded by the NSW Government, is comprised of seven cutting-edge facilities including a cell phenotyping core. This core provides functional characterisation for a range of cells including primary cardiomyocytes, cardiomyocytes differentiated from induced pluripotent stem cells, endothelial cells, heterologous expression systems and tissue preparations.

Our specific focus is on high throughput acquisition of data relating to electrophysiology, calcium homeostasis and mechanical properties of cells in health and disease. To achieve this, we have built the core around state-of-the-art technology including:

  • Nanion Syncropatch automated electrophysiology
  • Vala Sciences IC-200 Kinetic Imaging Cytometer
  • Axion Maestro Apex robotic multielectrode array system
  • Nanion Cardioexcyte automated contractility assay
  • PE Opera Phenix High Content imaging system

The role
As lead scientist in the cell phenotyping facility, the successful candidate will work on a range of projects with researchers from across the spectrum of the NSW cardiovascular community. You will have primary responsibility for ensuring optimal utilisation of our facilities including assistance with experimental design, data acquisition and data processing. You will have a strong back ground in physiology, engineering, or other relevant disciplines, and an ability to use this expertise to develop new applications of our suite of cutting-edge technology to extend the capabilities of the core facility.

Responsibilities
Duties and responsibilities include, but are not limited to:

  • Operation of high throughput phenotyping platforms
  • Methods development and validation
  • Training of staff and/or postgraduate students in analytical methods
  • Facility administration including equipment maintenance, devising SOPs, maintaining chemicals, consumables, etc.

Please apply if you satisfy the following criteria:

  • Tertiary qualification in a relevant discipline (eg. cell biology / physiology / bioengineering / pharmacology)
  • Significant expertise in cellular electrophysiology and calcium imaging
  • Demonstrated experience of methods development and validation, preferably in high throughput systems
  • Experience with analysing large data sets

What we offer:

  • Salary packaging
  • Bonus superannuation
  • State of the art facilities
  • Stimulating work setting focussed on cutting edge medical research
  • Collaborative team environment

We strive to ensure our staff and students enjoy a great working environment. We value and are committed to providing a working environment that embraces diversity and gender equity and promotes flexible working arrangements for staff to balance working requirements and personal needs.

Come and work with us and make a difference.

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Position

Lead Scientist - Cell Phenotyping