On behalf of the GROWTH Innovative Training Network, Gut Research is pleased to announce the recruitment of 8 Marie-Sklodowska Curie (MSCA) PhD students in the area of early life nutrition and chronic intestinal (inflammatory) disease.
Biological sciences › Biology, Biomedical Sciences, Biotechnology or Molecular Life Sciences.
Data Sciences › Bio-informatics.
Chemistry › Biochemistry.
Medicine › Surgery, Paediatrics or Internal Medicine.
8 PhD students (< 4 years of research experience at time of recruitment)
30 April 2019 18:00h – Europe/Brussels
- Gut Research BV (Amsterdam, The Netherlands, 1 PhD position)
- University Hospital Bonn (Germany, 2 PhD positions)
- Imperial College London (United Kingdom, 1 PhD position)
- Reckitt Benckiser (London, United Kingdom, 1 PhD position)
- Academic Medical Center (Amsterdam, The Netherlands, 1 PhD position)
- Cherry Biotech (Rennes, France, 1 PhD position)
- VU Medical Center (Amsterdam, The Netherlands, 1 PhD position)
TYPE OF CONTRACT
HOURS PER WEEK
OFFER STARTING DATE
Flexible starting June – October 2019
EU RESEARCH FRAMEWORK PROGRAMME
H2020 / Marie Sklodowska-Curie Actions / European Industrial Doctorates
MARIE CURIE GRANT AGREEMENT NUMBER
GROWTH website url: http://www.growth-horizon2020.eu/
The GROWTH consortium, funded by the European Commission (2019-2023), is made up to train a new generation of researchers working on new pathological insights, biomarker diagnostics and personalized nutritional interventions for intestinal failure in neonates and preterm infants. Academic and industry partners, covering various disciplines ranging from fundamental research to clinical paediatrics and analytical chemistry to organoid and gut-on-chip applications, have teamed up in the EU:
- Gut Research BV (The Netherlands)
- University Hospital Bonn (Germany)
- Imperial College London (United Kingdom)
- Reckitt Benckiser (United Kingdom)
- Academic Medical Center (The Netherlands)
- Cherry Biotech (France)
- VU Medical Center (The Netherlands)
- TNO Research (The Netherlands)
- Radboud University Medical Center (The Netherlands)
GROWTH is the first programme that proposes a prospective, deep analysis of the metabolic functions of bacteria and fungi in relation to neonatal health. The interplay between nutrition, gut microbiota, and its large number of metabolic and immune mediators plays an essential role in the development of gut immune homeostasis in early life. This interaction needs to be better understood because a disturbed immune function in the neonatal period is harmful for neonatal survival and enhances the risk of chronic inflammatory disease later in life.
The emergence of high-throughput technologies and the societal need for evidence-based interventions that fortify a healthy development of infants have spurred academic and industrial interest in the development of gut immune homeostasis in early life. These trends call for business-oriented researchers who can effortlessly adapt to innovative answers solving the persistent and novel challenges innutrition-host-microbe interactions in early life.
The research and training agenda falls into several interconnecting themes:
- Study how the ecology of the gut microbiome is constructed during the first stages of life and how this leads a disturbed immune function in the neonatal period.
- Perform (un)targeted analysis of the faecal metabolome and develop fecal assays.
- Develop bio-informatics approaches for mapping the microbiome and mycobiome and their metabolomics functions.
- Create a metabolic phenotype for intestinal failure (including sepsis and NEC) and study the role of these multifactorial pathways in its initiation.
- Establish advanced microfluidic gut-on-a-chip model systems, enteric glial cells and epithelial co-cultured mini-gut organoids, as well as replicable animal models to study the mechanism of action and deliver therapeutic targets for novel nutritional formulae.
GROWTH capitalizes on several large cohorts of preterm and term infants. One cohort encompasses a collection of daily fecal samples (>17.000) of 1,500 preterm and term neonates combined with a close clinical follow-up on health status from 9 Neonatal Intensive Care Units in The Netherlands.
In addition to undertaking a doctoral research degree, the PhD students will engage in a series of collaborative research and training events to develop advanced skills and expertise in tackling challenges linked to innovations in early life nutrition to prevent disease.
It is a requirement of the funding that applicants cannot have spent more than 12 months in the country of the hosting institute in the 3 years immediately prior to recruitment. Furthermore, GROWTH entails a European Industrial Doctorate program that requires PhD students to spend at least 50% of their time (18 months) in the non-academic sector.
REQUIRED EDUCATION LEVEL
A degree (MSc, or equivalent) in Health and/or Life Sciences (Biology, Microbiology, Molecular Biology, Immunology, Biomedical Sciences, Biochemistry or closely related fields) or Data Sciences (Bio-informatics, Machine Learning) or Medicine (Surgery, Paediatrics or Internal Medicine). Candidates in the final stages of obtaining their degree are eligible to apply
ENGLISH: Excellent, both written and spoken.
We expect a Master´s degree (or equivalent) in Health and Life Sciences, Data Sciences or Medicine. Furthermore, the applicant should be able to perform team-oriented as well as independent work. Desirable methodological skills: excellent background in molecular biology, biochemistry, cell biology, immunology and/or microbiology, hands-on knowledge of analytical methods.
The per annum MSCA PhD student living and mobility allowance (plus family allowance if applicable, family status is assessed at recruitment) is in line with EU-MSCA requirements. This amount will be subject to tax and employee’s National insurance deductions and will be paid in EURO.
Complete applications in English should include the GROWTH Application Form and its mandatory attachments. Please note that applications that do not meet these requirements WILL NOT BE CONSIDERED.
Please send the complete package as 1 PDF file via email to firstname.lastname@example.org 30 April 2019 18:00h – Europe/Brussels.
Please familiarize yourself with the currently available projects (www.growth-horizon2020.eu) and the selection process and timelines as described above. Selected applicants will be invited to an Onsite Recruitment Event in Amsterdam on 13 May 2019. Awarding decisions will be announced shortly thereafter, and candidates are expected to be available to start their projects between June and October 2019.