KTH Royal Institute of Technology in Stockholm has grown to become one of Europe’s leading technical and engineering universities, as well as a key centre of intellectual talent and innovation. We are Sweden’s largest technical research and learning institution and home to students, researchers and faculty from around the world. Our research and education covers a wide area including natural sciences and all branches of engineering, as well as architecture, industrial management, urban planning, history and philosophy.
You will work at the Division of Protein Engineering (https://www.kth.se/pro/proteineng) in the group Next Generation Protein Therapeutics (https://www.kth.se/pro/proteineng/next-generation-protein-therapeutics). The research focuses on the design and engineering of new functions and properties of natural and artificial proteins, with applications in many different areas, for example for the development of biological drugs.
A main focus is directed evolution, i.e. the use of large collections of protein variants expressed on, for example, microorganisms from which proteins with desired properties can be selected.
The work will include development and characterization of new protein-based reagents, with a long-term goal of evaluating their potential for future drugs in various disease areas such as cancer and dementia. The work will include laboratory research in protein chemistry. Examples of methods may include: selection of affinity reagent from protein libraries with for example phage display technology, production and purification of recombinant proteins, biotechnological methods for analysis of purity, secondary structure, heat stability, biomolecular interactions, cell binding, etc. For more information about our research see: https://www.kth.se/pro/proteineng/next-generation-protein-therapeutics. This postdoctoral position is a full-time employed position for one year with a possible one-year extension.