Salary: Grade 7: £32,236 - £39,609 p.a.
An opportunity has arisen for a Postdoctoral Researcher to join Sir Walter Bodmers research group working on the genetics, cell biology and differentiation of colorectal cancer, with a special interest in the development of novel immunological therapies. Your main role will be to develop and carry out preclinical testing of bispecific monoclonal antibodies targeted against tumour determinants as well as T lymphocyte engaging surface markers. This will involve the use of the laboratorys extensive collection of more than 120, mostly fully characterised, colorectal cancer (CRC) derived cell lines as well as CRC organoids derived from freshly obtained CRC biopsies. You will also be expected to help in other projects on aspects of the control of differentiation and myofibroblast/epithelial cell interactions being undertaken by graduate students and visitors in the laboratory. This will include providing guidance to less experienced members of the research group.
You will adapt existing, and develop new, scientific techniques and experimental protocols and will be expected to develop and contribute ideas for new research projects.
You will hold (or be working towards) a relevant PhD/DPhil in biology, molecular biology or a related science and will have a high level of technical competence in standard molecular and cell biological techniques, including especially cell culture and, for example, western blotting, immunofluorescence, transfection, DNA and RNA isolation.
This is a full-time post offered for 14 months in the first instance.
All applicants must complete a short application form, upload a CV and supporting statement.
The closing date for applications is 12.00 noon on 24 April 2019.