The DFCI Center for Immuno-Oncology (CIO) is a multi-disciplinary group dedicated to the discovery, development, and first-in-human clinical trials of novel immunotherapies. The CIO Immune Assessment Laboratory (http://ciolab.dfci.harvard.edu/) is accepting applications for a Research Staff Scientist to coordinate and direct basic and translational biomarker research in immuno-oncology. Such an individual will work closely with the directors of the CIO to develop biomarkers to guide patient selection and therapies in the field of cancer immunology. Responsibilities will include overseeing laboratory technicians, reviewing and preparing data, presenting at CIO group meetings and at national meetings, and contributing to high-impact publications. We are looking for an experience individual with strong knowledge of flow cytometry and/or CyTOF. Qualified individuals will have a Bsc/MS with applied professional experience or PhD/Post-doc in a basic science or translational clinical research laboratory. A preferred candidate will be comfortable working independently and collaboratively and have strong management skills.
- Work with DFCI PIs and research staff to design and develop biomarker experiments and protocols
- Offer scientific expertise in analyzing mechanistic and biomarker endpoints for clinical trials related to cancer immunotherapies
- Assist with the development, validation and deployment of CyTOF for clinical trials within the NIH-funded CIMAC network https://cimac-network.org/)
- Oversee and manage project goals, timelines and deliverables.
- Manage the work efforts of one or more technicians. Completes performance appraisals
- Responsible for training and mentoring other lab personnel and researchers
- Contribute to collaborative projects, co-author publications, multi-center grant applications, and conference presentations.
- Communicate new findings in a translational research environment strongly focused on discovery and development of novel immunotherapies to improve patient care.
- Bsc/MS with applied professional experience (> 3 years) or PhD level candidate with experience (> 1 year) in immunology, oncology, or life sciences required.
- Basic tissue culture and molecular biology skills (e.g. qPCR, PCR) required
- Flow Cytometry experience required
- Flow Cytometry data analysis (e.g. FlowJo, Cytobank) required
- Mass Cytometry (CyTOF) experience preferred
- Excellent personal task management skills and high level of self-motivation
- Excellent verbal and written communication skills
- Willingness to contribute to collaborative projects and co-author publications.
- Strong analytic and problem-solving skills, with experience with data acquisition, data analysis, data presentation and documentation
- Demonstrated ability to multitask and troubleshoot problems
- Strong team player and ability to work well with diverse faculty and staff