Postdoctoral Research Associate

Postdoctoral Research Associate

University of Cambridge

Cambridge, United Kingdom

Postdoctoral Research Associate: Chemists/Chemical biologists to study DNA base modifications and their epigenetic functions (Fixed Term)
Department of Chemistry
Reference: MA16981

Fixed-term: The funds for this post are available for 2 years in the first instance.

We seek two postdoctoral scientists to work with Professor Sir Shankar Balasubramanian on a Wellcome Trust-funded programme to investigate the structure and function of chemically modified nucleic acid bases. This is an interdisciplinary project that encompasses the use of organic and biophysical chemistry, chemical biology and molecular biology on DNA and on the genome. See for further information.

We look to appoint chemists or chemical biologists to carry out research on how chemically modified bases affect the structure and function of DNA. The investigations will involve a consideration of the chemistry and enzymology of nucleic acids, protein-DNA interactions, epigenetics, chromatin structure and transcription. This will enable us to gain a deeper understanding of the function of base modifications and their involvement in regulating gene expression in normal and disease states using cellular models from human, and mouse and also parasite models.

The successful candidates will have a capacity for innovation and creativity. Strong communication skills and the ability to work effectively as part of a multi-disciplinary team will be important. Experience in nucleic acid chemistry and working in an interdisciplinary environment with molecular/cell biologists or biochemists would be an advantage.

Candidates should have (or be about to receive) a PhD in a relevant discipline.
The positions are available immediately.

Previous applicants need not apply.

To apply online for this vacancy and to view further information about the role, please visit:

Closing date: 18 April 2019

Please ensure that you upload a 2-page Curriculum Vitae (CV), a covering letter that explains your motivations for the position and your publications list in the Upload section of the online application. If you upload any additional documents that have not been requested, we will not be able to consider these as part of your application.

For queries regarding this post, please contact Jo Lockhart, PA to Professor Sir Shankar Balasubramanian, email:

Please quote reference MA16981 on your application and in any correspondence about this vacancy.

The Department holds an Athena SWAN silver award for women in science, technology, engineering, mathematics and medicine.

The University actively supports equality, diversity and inclusion and encourages applications from all sections of society.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Please apply via recruiter’s website.

Quote Reference: Reference: MA16981