Postdoc - Gene expression regulation in stem cells and cancer

Postdoc - Gene expression regulation in stem cells and cancer

University of Zurich

Zurich, Switzerland

Postdoc – Gene expression regulation in stem cells and cancer

Description:
We are seeking to recruit a passionate postdoctoral researcher to join an interdisciplinary project on the role of RNA-binding proteins and alternative translation in stem cells and cancer. The project combines the group’s expertise in functional genomics, gene expression regulation and mouse models to understand how translation is reprogrammed in disease.

Responsibilities:
We are looking for a creative and determined candidate with strong analytical skills and an interest in applying systems biology approaches to understand the role of gene expression regulation in stem cells and cancer. You will be working in a collaborative and interdisciplinary, young team that tackles complex biological problems and draws from the fields of tumor and stem cell biology, gene expression regulation, molecular biology, bioinformatics, and biomedicine. You will coordinate and overlook in vivo functional genomics screenings in mice using the ultrasound-guided in utero lentiviral injection system, analyze complex data sets, characterize new genes surfacing in the screen, supervise MSc/PhD students and publish as lead author in highly visible journals. Existing skills with regard to translational control or RNA biology would be an advantage.
Our laboratory carries out interdisciplinary research at the interface between cancer biology, stem cell biology and regulation of protein synthesis and is part of a dynamically evolving new campus of the ETH and University of Zurich, Switzerland.

Qualifications:
Applicants for the postdoctoral researcher position should hold a PhD or MD-PhD in life sciences with a strong background in RNA biology, translational control, systems biology or a related discipline and should have a solid publication record in peer-reviewed journals.
Specific qualifications include:

  • Excellent communication skills with a focus on teamwork, willingness to work closely with team members and potentially co-mentor PhD and master students
  • Driven by scientific curiosity
  • Ability to work independently and complete tasks efficiently, strong work ethic
  • Expertise in the analysis of high dimensional data sets, statistical analysis, and/or programming would be desired
  • Existing skills with regard to mouse models of cancer, RNA biology, protein synthesis regulation, stem cell biology or functional genomics will be an advantage.
  • Excellent proficiency in English (German is optional)

We offer:
We offer a great opportunity in the international, dynamic and vibrant research environment of the Institute for Regenerative Medicine at the University of Zurich. Outstanding working conditions at the University of Zurich, state-of-the-art infrastructure, a stimulating research environment that actively promotes dynamic interactions between scientists and a very competitive salary. The position is available starting May 1, 2019 or upon agreement.

Contact:
Interested applicants are encouraged to send their application documents (cover letter, CV, contact information of 2-3 references) as one pdf document per e-mail to Prof. Ataman Sendoel (email: ataman.sendoel@uzh.ch). Applications will be considered on a rolling basis until the position is filled. For further information about the lab, please visit www.sendoellab.org. Closing date: April 30, 2019.

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Postdoc - Gene expression regulation in stem cells and cancer