Three Postdoctoral / Staff Scientist Positions (m, f, d) in CRISPR/Cas screens and proteomics

Three Postdoctoral / Staff Scientist Positions (m, f, d) in CRISPR/Cas screens and proteomics

Goethe University Frankfurt - Institute of Biochemistry II

Frankfurt am Main, Germany


We are looking for postdoctoral fellows or staff scientists in the recently established Frankfurt CRISPR/Cas screening center (FCSC) at the Institute of Biochemistry II, Goethe University, Medical Faculty, Frankfurt, Germany (, located at the Campus Niederrad – University Hospital Frankfurt.

Based on a novel technology to generate gene perturbation reagents, developed at the Goethe University (, FCSC provides innovative CRISPR/Cas reagents and performs high-throughput screening utilizing single and multiplexed gRNA libraries.

The newly recruited team members will be involved in the generation of CRISPR/Cas reagents, as well as cell culture-based CRISPR/Cas screenings, high-throughput sequencing (NGS) and data analysis of CRISPR/Cas screens. CRISPR/Cas screens will be coupled to mass spectrometry, as collaboration effort with the Institute´s proteomics platform (

Three positions are available immediately, for the initial duration of 2 years.

The candidates should have a PhD degree in any field of life sciences with an excellent knowledge of molecular and genomics biology, as well as profound knowledge in computational and statistical analyses. Prior experience with mammalian cell culture (biosafety 1 and 2) and molecular biology methods is mandatory. Prior experience with NGS methods and analysis of high-throughput datasets is strongly desirable. For mass spectrometry position, proficiency in sample preparation, measurement and bioinformatics analysis, together with expertise in the use of Thermo mass spectrometers Orbitrap (HF and Lumos) are preferred.

The official language of the FCSC is English. The designated salary for the position is based on the TV-G-U, the limitation of the contract is based on the regulations of the “Wissenschaftszeitgesetz” in conjunction with the “Hessische Hochschulgesetz”. The Goethe University is committed to increase the proportion of female scientific staff and therefore encourages women particularly to apply. Applications of scientists from abroad are explicitly requested. Severely disabled applicants with equal qualification and aptitude will be given preferential consideration.

Applications including CV and cover letter describing motivation should be sent to FCSC team leader Dr. Koraljka Husnjak (
In addition, two reference letters must be sent directly to


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Three Postdoctoral / Staff Scientist Positions (m, f, d) in CRISPR/Cas screens and proteomics