Research Fellow - Cancer Genomics/Computational Biology

Research Fellow - Cancer Genomics/Computational Biology

Charité - Universitätsmedizin Berlin

Berlin, Germany

The Charité – Universitätsmedizin Berlin is a joint medical faculty, which serves both Freie Universität Berlin and Humboldt Universität zu Berlin. As one of the largest university hospitals in Europe with an important history, it plays a leading role in research, teaching and clinical care. The Charité university hospital has also made a name for itself as a modern business with certifications in the medical, clinical and management fields.

The ECRC, Klinik für Pädiatrie m.S. Onkologie und Hämatologie, Charité is seeking for an

Research Fellow – Cancer Genomics/Computational Biology
Ref.no. DM.209.18b

The research group of Anton Henssen at the ECRC Research Center of the Max Delbrück Center for Molecular Medicine (MDC) in Berlin, Germany is seeking a post-doctoral research fellow in cancer genomics/computational biology. The lab studies the causes of genomic instability in pediatric solid tumors with a focus on mobile genetic elements such as transposons and circular DNA (eg. Henssen A. et. al. Nature Genetics 2017).

Your area of responsibility
Our Pediatric Oncology Reseach Lab at the Department of Pediatric Hematology, Oncology at the Experimental and Clinical Research Center (ECRC) is closely affiliated to the Helmholtz Institute, Max Delbrück Center (MDC) for Molecular Medicine and the Berlin Institute of Health (BIH). The main focus of all research programs is to improve cure rates for patients suffering from childhood cancer by combining basic, translational and clinical research.

The main interest of our research group is to better understand the causes and consequences of genomic instability in childhood solid tumors. For this purpose, the group relies on high-throughput sequencing methods such as DNA, RNA and ChIP sequencing from pirmary patient samples as well as from Single cells (e.g. Henssen A. et al., Nature Genetics 2017).

We are looking for a motivated research scientist with a background in computational biology and an interest in cancer biology.

The successful applicant will 1) develop new methods/ apply published methods for the analysis of complex structural variants in cancer genomes, 2) plan and perform analyses of Illumnina, SMRT and Nanopore sequencing data within research projects of our group, 3) structure and manage high-throughput data and 4) work on existing collaborations with other computational biology groups (eg. at Max Planck Institute) as well as establish new collaborations

Your Profile
- Recent graduate (PhD) or research scientist (PhD not necessary) in cancer biology, bioinformatics, statistics, physics or any other field with relevance to biology/computational biology
- Proficiency in basic programming fundamentals for data analysis (preferably in R and in one of the scripting languages such as Perl/Python)
- Ability to collaborate and communicate complex technical concepts (preferably in English, German not necessary).
- Understanding of basic cancer molecular biology principles is highly preferred

Start
immediately

Length of employment
31.08.2021

Working Time
39 hrs

Pay Scale
E13

Acc. to collective agreement
TVöD VKA-K

Employees are grouped into pay scales according to their qualifications and personal requirements. You can find our collective bargaining agreements (Tarifverträge) here: https://www.charite.de/en/careers/

DIE CHARITÉ – UNIVERSITÄTSMEDIZIN BERLIN makes its human resources decisions based on suitability, competence and professional performance. At the same time, it strives to increase the percentage of women in management positions and takes this into consideration where candidates are equally qualified within the limits of what is legally possible. Applications from people with a migrant background are also explicitly welcome. Severely disabled applicants are given preferential consideration in the case of candidates with equal qualifications. A certificate of conduct, or an extended certificate of conduct, if applicable, must be submitted. Any travel expenses incurred cannot be reimbursed. Data protection notice: Charité points out that personal data is stored and processed as part of the application process in different areas of Charité (e.g. faculty, staff committee, human resources department). urthermore, the data may be transferred or processed within the group as well as in locations outside the group (e.g. authorities) to protect legitimate interests. By applying, you agree to our data protection regulations and terms of use, which you can find here:
https://www.charite.de/service/datenschutz/bewerbungsverfahren/

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Research Fellow - Cancer Genomics/Computational Biology