Postdoctoral position in Pharmacology, Biochemistry and Biomedical Sciences at Case Western Reserve University
We are interested in understanding how our cells protect the genome integrity. This is critical, as defects in this process have been reported to cause many human diseases such as cancer, premature aging, neurodegeneration, etc. Further, signaling pathways responding to and repairing DNA damage hold the promise of being developed into effective therapeutic strategies, for instance, in cancer treatment.
We use pharmacological, biochemical, and genetic tools to understand molecular mechanisms underlying the DNA damage response, and their implications in the pathogenesis and treatment of human cancer (e.g.,Molecular Cell, 19, 607-618, 2005.Molecular Cell, 35, 442-453, 2009.Cancer Research, 72, 3786-3794, 2012. PNAS,111, 17456-61, 2014. JBC, 291, 12951-12959, 2016. JBC,292:5992-6003, 2017). The department also has strong expertise in structural biology. (http://pharmacology.case.edu/department/Faculty/Primary/Labs/Zhang/Default.aspx)
Self-motivated individuals who have a recent PhD degree are encouraged to apply. Strong background in biochemistry (Western blotting, immunofluorescence, immunoprecipitation, etc) and molecular (PCR, cloning and vector generation, etc.) and cellular (cell culture, transfection, and so on) biology is required.
Interested applicants should forward their CV and a list of three references through email to:
Dr. Youwei Zhang, Ph.D.
Department of Pharmacology,
Case Western Reserve University ranks ~37 of all universities and colleges in the US. Cleveland is a nice city with very affordable living cost.