Research Technician

Research Technician

Howard Hughes Medical Institute (HHMI)

Seattle, WA, United States

Job Description

About HHMI

Howard Hughes Medical Institute (HHMI) is a science philanthropy whose mission is to advance biomedical research and science education for the benefit of humanity. We empower exceptional scientists and students to pursue fundamental questions about living systems, and work to share scientific discoveries with researchers, students, and science-curious individuals around the world.

Founded in 1953 by aviator and industrialist Howard R. Hughes, HHMI is headquartered in Chevy Chase, Maryland, and employs more than 2,500 people across the U.S. Visit to learn more about working at HHMI.

We have an exciting opportunity for a Research Technician for the Malik Lab in the Basic Sciences Division. It is ideally suited for someone with substantial yeast genetics and molecular biology experience who is comfortable working independently to design and execute experiments, particularly in bringing new methodologies to the lab. This technician will have the opportunity to carry out their own research project under the supervision of a senior researcher in the lab and will earn authorship on any scientific papers to which they contribute.



  • The primary focus of this position is to identify and characterize natural restriction factors of a selfish parasite found in many yeasts. The work will involve extensive molecular biology and genetics (e.g. molecular cloning, DNA extractions, sequencing), and routine handling of bacterial and yeast cultures.
  • Secondary responsibilities include lab management (e.g. maintaining media stocks), ordering scientific lab supplies, and maintaining equipment.
  • Based on the interest and ability of the technician, s/he may also be solely responsible for the development and execution of additional yeast genetics research projects. Successful projects in which the candidate participates may lead to authorship on scientific publications.
  • Handling microbial cultures, molecular biology, and routine bioinformatics will be required.




  • Specific experience with DNA extraction, PCR, gel electrophoresis, molecular cloning, yeast and bacterial transformation, aseptic technique, and handling cultures is required.
  • Strain construction experience required, with strong preference given to candidates with both PCR and CRISPR-based technologies.
  • Participation in lab meetings and presentation of data will be required.
  • Education requirements: a bachelor’s in biology or a related discipline in a laboratory environment, or equivalent in education and experience.
  • Excellent communication skills are a must. Superior verbal and written communication and routine computer skills (PC/Mac) are necessary.
  • Must be able to work independently on a model system not used extensively in the laboratory; demonstrating initiative and competence in identifying new protocols and bringing new methodology into the laboratory.
  • Must work well in an interdisciplinary environment, collaborating with a team of scientists at the interface of evolutionary, molecular, and microbiology.
  • Meticulous attention to detail, and communication skills are essential.
  • Superior organizational skills in recordkeeping, multitasking, prioritizing responsibilities, time management, and an ability to interact with all levels of staff are requirements. 


HHMI is an Equal Opportunity Employer


Required Skills

Required Experience

Please apply via recruiter’s website.

Quote Reference: Howard Hughes Medical Institute (HHMI)-hhmi-963-908