PhD scholarship in High Throughput Organoid Tissue Systems

Technical University of Denmark (DTU)

2800 Kgs. Lyngby, Denmark

Organovir is an Innovative Training Network (ITN) that focuses on the use of organoid technology for viral pathogenesis studies and anti-viral testing. For this ITN we will provide 15 Early Stage Researchers (ESRs) with the opportunity to be trained within a consortium of public and private experts that will enable them to lead innovation in the field of organoids for virus research. The starting date of the research projects is 1 September 2019.

In this specific project, we focus on making scalable hydrogel system for high throughput screening and increased cell or organoid functionalities. During this project, you will be focussing on the following research objectives:

  • To construct a stackable co-culture systems with flexible hydrogels
  • To scale the stackable system into 96-well plate format
  • To place organoids behind epithelial layer and/or endothelial layer to simulate coupled organ system
  • Model virus propagation in the system
  • Provide chemical and 3D cues to improve organoid function and organisation.

Responsibilities and tasks
The candidate will be responsible for the development of the system and testing the systems for compatibility with organoid cultures. The candidate is expected to be open to collaborations and actively participate in the training network. Specifically, this includes collaborating with other PhD students in the program and in at the departments and to go to two secondments:

  • A three-month secondment Academisch Medisch Centrum bij de Universiteit van Amsterdam (location: Amsterdam, the Netherlands) focused on transfer of stackable hydrogel technology
  • A three-month secondment with the University of Jagiellonski (location: Krakow, Poland) focused on learning about cocultures of fibroblasts and immune cells.

Qualifications
Candidates should have a two-year master's degree (120 ECTS points) or a similar degree with an academic level equivalent to a two-year master's degree.

Organovir is looking for research candidates who are highly motivated and enthusiastic with a flexible, pro-active team spirit and a recent Master degree in the field tissue engineering or similar. Interest and experience in 3D printing, microfluidics, and working with mammalian cell cultures is an advantage. The candidate is required to be proficient in the English language and should be in the first four years (full-time equivalent) of their research careers.

Due to the grant mobility aspects, the applicant must not, at the time that he/she is selected by the host institution, have resided or carried out their work and/or studies in the country of the host institution for more than 12 months in the 3 years immediately prior to their recruitment.

Approval and Enrolment
The scholarship for the PhD degree is subject to academic approval, and the candidate will be enrolled in one of the general degree programmes at DTU. For information about our enrolment requirements and the general planning of the PhD study programme, please see the DTU PhD Guide.

Assessment
The assessment committee will consist of members of the Organovir research leader team.

We offer
DTU is a leading technical university globally recognized for the excellence of its research, education, innovation and scientific advice. We offer a rewarding and challenging job in an international environment. We strive for academic excellence in an environment characterized by collegial respect and academic freedom tempered by responsibility.

Salary and appointment terms
The appointment will be based on the collective agreement with the Danish Confederation of Professional Associations. The allowance will be agreed upon with the relevant union. The period of employment is 3 years.

You can read more about career paths at DTU here.

Further information
Further information may be obtained from Martin Dufva, tel.: +45 51 33 37 53.

You can read more about DTU Health Tech at www.healthtech.dtu.dk

Application
Please submit your online application no later than 31 March 2019 (local time).

Apply online at www.career.dtu.dk.

Applications must be submitted as one PDF file containing all materials to be given consideration. To apply, please open the link "Apply online", fill out the online application form, and attach all your materials in English in one PDF file. The file must include:

  • A letter motivating the application (cover letter)
  • Curriculum vitae
  • Grade transcripts and BSc/MSc diploma
  • Excel sheet with translation of grades to the Danish grading system (see guidelines and Excel spreadsheet here)


Candidates may apply prior to obtaining their master's degree but cannot begin before having received it.

Applications and enclosures received after the deadline will not be considered.

All interested candidates irrespective of age, gender, race, disability, religion or ethnic background are encouraged to apply.

DTU Health Tech engages in research, education, and innovation base on technical and natural science for the healthcare sector. The Healthcare sector is a globally expanding market with demands for the most advanced technological solutions. DTU Health Tech creates the foundation for companies to develop new and innovative services and products which benefit people and create value for society. DTU Health Techs expertise spans from imaging and biosensor techniques, across digital health and biological modelling, to biopharma technologies.


DTU is a technical university providing internationally leading research, education, innovation and scientific advice. Our staff of 6,000 advance science and technology to create innovative solutions that meet the demands of society, and our 11,200 students are being educated to address the technological challenges of the future. DTU is an independent academic university collaborating globally with business, industry, government and public agencies.

Please apply via recruiter’s website.

Quote Reference: Technical University of Denmark-technical_uni_of_denmark-52490

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