Umeå Plant Science Centre (UPSC) is one of the strongest research environments for basic plant research in Europe. Research at UPSC covers a wide range of disciplines in plant biology including ecology, genetics, physiology, biochemistry, cell biology and molecular biology (see www.upsc.se). The postdoctoral fellowship is going to be placed at the Department of Plant Physiology, which is part of Umeå Plant Science Centre. Our common goal is to understand plants ability to adapt and acclimate to a changing world. We are looking for a highly motivated postdoc for the project “Pathogen resistance is dependent on changed metabolism” in Johannes Hanson’s research group.
Energy levels is monitored to optimize cellular metabolism and physiology in all living cells. In plants this is regulated primarily by kinases Target of Rapamycin (TOR) and Snf1 related kinase 1 (SnRK1) with opposing activities. The kinases operate at cellular level but regulate tissue specific processes as well as general physiology of the plant. The candidate will join a team focused on understanding the molecular details of these signaling pathways. The project is focused on how metabolism is affected by and affects plant defense responses. We have taken an Arabidopsis cell culture-based approach to be able to study the signaling pathways minute by minute. We want to understand how a specific group of plant transcription factors are affected by pathogen derived effectors to direct metabolic change in favor of the attacking pathogen. By understanding the mechanism, we hope to increase plant resilience to pathogen attack. The project involves RNASeq and Chromatin immunoprecipitation approaches as well generation of transgenes and transgenic cell lines using Crispr/CAS9. Changed metabolism will be analyzed using GC- and LC-MS instrumentation in close cooperation with the Swedish Metabolomic Centre (www.swedishmetabolomicscentre.se).
The stipend is granted for 2 years with start 1 June 2019 or by agreement. The tax-free stipend is financed by the Kempe foundation and amounts to 288 000 SEK per year.
Successful candidates will have a PhD degree, or equivalent, in Plant molecular biology or biochemistry. To be eligible for this fellowship, you should have completed your doctoral degree maximum three (3) years before the end of the application period unless certain circumstances exists. The candidate should have extensive laboratory experience with biochemical methods and molecular biology. Experience with plants as model system is an advantage. Experience with cell lines or Mass-spectrometry as well as proficiency using the R statistical programming language is an advantage. The candidate should also have far-reaching interest in inter- and intra-cellular signaling mechanisms. The ability to be independent as well as cooperate in a team, and good skills in the English language, are required. We value your creativity, ability to communicate and take initiatives.
The application should contain:
1. A personal letter that describes your qualifications, research interests, and motivation for application
2. CV with full publication list
3. Copies of doctoral degree certificate and other relevant degree certificates and grades,
4. Copy of doctoral thesis,
5. Contact information of two referees,
6. Other documents wished to be claimed.
Your complete application, marked with reference number FS 2.1.6-447-19, must be submitted as a pdf-document to firstname.lastname@example.org (state the reference number as subject) before 1 May, 2019.
Further information can be obtained from Dr. Johannes Hanson, email@example.com
We look forward to receiving your application!