Postdoctoral Fellow

Postdoctoral Fellow

Weill Cornell Medicine (WCM), Cornell University

New York, NY, United States

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<!—StartFragment—>

The Englander
Institute for Precision Medicine at Weill Cornell Medicine is seeking a postdoctoral
fellow with a background in cancer biology or a related field to join our team.
 
We are seeking a dynamic
individual who will be responsible for designing and executing studies focused
on circulating tumor cells and organoid development. 

 

A priority of the Englander Institute for Precision Medicine is to
optimize and implement new innovative cancer tests that can be utilized to (i)
identify cancer biomarkers in the circulating tumor cells that tell oncologists
if a patient’s cancer is progressing and which therapies will be most effective
for that patient (ii) develop targeted clinical trials for patients with highly
recurrent mutations; and (iii) enhance scientists understanding of the complex
mechanisms of tumor cell mobility.
Our research is focused on the
utilization of patient derived models of cancer, the definition of distinct molecular
classes of cancer using genomic data from human samples, studying the functional
impact of novel genetic and epigenetic alterations in preclinical models, and investigating
the potential to translate these findings to clinical relevance.  

The work will be performed under the supervision of Dr. Olivier
Elemento, Director of Englander Institute for Precision Medicine. The candidate
will collaborate with a multidisciplinary team composed of basic scientists,
computational biologists, pathologists, and medical oncologists, with
significant resources for bioinformatics support and studies in human tissues.

The candidate is expected to perform experiments exploring high-throughput
drug screening platforms, organoid model development, tumor microenvironment,
tumor metabolism, and genetic and epigenetic alterations using a variety of preclinical
model systems including cell lines, xenografts, and genetically engineered
mouse models.  
A desire to develop
and implement new methodologies is highly advantageous.  There will be
numerous opportunities for training to complement current skills, and we
envision numerous collaborations with other outstanding scientists.

Applicants should have experience
in a related field, together with
a
strong publication record, and strong previous
research experience in signal transduction, transcriptional control, genomics
and bioinformatics, or related fields. Experience with several of the following
activities would be desirable: characterization of
genetically
engineered mouse models, work with patient-derived xenografts and culture of
primary cells. 
Initial salary is commensurate with
experience.  Applying for independent
funding is not required, but is strongly encouraged for the career development
of the candidate.

 

Position Activities

<!—[if !supportLists]—>·  Perform experiments exploring high-throughput drug screening
platforms, organoid model development, tumor microenvironment, tumor
metabolism, and genetic and epigenetic alterations using a variety of
preclinical model systems including cell lines, xenografts, and genetically
engineered mouse models

 

Requirements

<!—[if !supportLists]—>·       <!—[endif]—>PhD in biological sciences, biochemistry or related
field

<!—[if !supportLists]—>·       <!—[endif]—>Minimum 2 years laboratory experience

<!—[if !supportLists]—>·       <!—[endif]—>Strong publication record

<!—[if !supportLists]—>·       <!—[endif]—>Driven
and Self-motivated – Willingness to tackle and drive execution of challenging
projects

<!—[if !supportLists]—>·       <!—[endif]—>Ability
to learn and deliver work in fast-paced and diverse environment

<!—[if !supportLists]—>·    Comfortable
with communicating and working alongside a diverse team of scientists and
medical professionals

<!—[if !supportLists]—>·       <!—[endif]—>Preferred experience: characterization
of
genetically engineered mouse models, work with
patient-derived xenografts and culture of primary cells

<!—[if !supportLists]—>·        <!—[endif]—>Excellent organization and documentation skills

 

Desired Skills

<!—[if !supportLists]—>·       <!—[endif]—>Strong communication skills and an ability to
interact well with others

<!—[if !supportLists]—>·       <!—[endif]—>Detail-oriented

 

 

<!—EndFragment—>

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Postdoctoral Fellow