A three year postdoc position in innate immunology and use of genome-wide CRISPR screening tools

A three year postdoc position in innate immunology and use of genome-wide CRISPR screening tools

Aarhus University (AU)

Aarhus C, Denmark

Cell death is emerging as a central player in innate immunity, but the mechanisms involved are poorly understood. A three year postdoc position at Aarhus University is open for a project aiming to identify molecular mechanisms mediating cell death in innate immunity. We will base the project on genome-wide CRISPR-based screenings, and will follow up the findings with in-depth mechanistic characterization, and validation of physiological importance in relevant model systems.

The successful applicant is expected to have interest and skills in both fundamental immunology and use of CRISPR genome editing tools. We are looking for a highly motivated and ambitious person who is interested in developing the project to the highest level. The project involves two collaborating labs, and will also engage internal and external collaborations. Therefore, applicants with good collaboration skills will be preferred. We offer a world-leading research environment in innate immunology and genome-editing technology. We expect that the person employed will take his/her share in the further development of the local environment.

Selected publications from the host laboratories:
  • Nandakumar et al. Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signaling. Nature Microbiology. 2019.
  • Paludan et al. DNA-stimulated cell death: implications for host defence, inflammatory diseases and cancer. Nature Reviews Immunology. 2019.
  • Haslund et al. Dominant-negative SERPING1 variants cause intracellular retention of C1 inhibitor in hereditary angioedema. Journal of Clinical Investigation. 2019.

For further questions, please contact:
Professor Søren Riis Paludan (srp@biomed.au.dk)
Professor Jacob Giehm Mikkelsen (giehm@biomed.au.dk)

The position is open from August 1 or soon thereafter and is funded by a grant from the European Research Council (ERC).

Terms of employment
Your application must include the following:
  • Motivated application
  • Curriculum Vitae
  • Diploma
  • A list of publications
  • A teaching portfolio. We refer to Guideline on the use of teaching portfolios
  • A maximum of five of the publications of greatest relevance to the job may be submitted
  • References/recommendations can be uploaded separately in the e-recruitment system
  • Template for applicant - postdoc must be completed and uploaded under ‘Extra documents’

We refer to the faculty’s Guidelines for applicants.

The assessment committee may decide to include non-submitted material in its statement. In such cases, you will be informed and obliged to submit material, unless your application is withdrawn.

Applications submitted through channels other than the online application form or applications which are not received by the application deadline will not be considered.

All interested candidates are encouraged to apply, regardless of their personal background.

International applicant?
Aarhus University offers a broad variety of services for international researchers and accompanying families, including relocation service and career counselling to expat partners. Please find more information about entering and working in Denmark here. Aarhus University also has a Junior Researcher Development Programme. You can read more about it here.

Aarhus University
Aarhus University is an academically diverse and research-intensive university with a strong commitment to high-quality research and education and the development of society nationally and globally. The university offers an inspiring research and teaching environment to its 39,000 students (FTEs) and 8,000 employees, and has an annual revenues of EUR 884 million. Learn more at www.au.dk/en

Application Deadline:
14 April 2019

Please apply via recruiter’s website.

Quote Reference: Aarhus University-aarhus_university-52448