Job title: Research Officer
Salary: £34,189 to £39,609 per annum, together with NUSS pension
Contract: Fixed-term position until 30th September 2020
The Molecular Cardiology group in Swansea University Medical School invites applications for two post-doctoral research associates to support and contribute to a British Heart Foundation-funded programme of work on sudden death-linked mutations in the cardiac calcium release channel (ryanodine receptor, RyR2). RyR2 is a massive tetrameric channel that regulates the release of intracellular calcium stored in the sarcoplasmic reticulum (SR) into the cytoplasm to trigger the contraction of heart cells. Genetic mutations or acquired defects in RyR2 disrupt normal channel structure and interfere with channel opening and closing. This causes abnormal calcium release from the SR and the breakdown in normal heart rhythm (arrhythmia) leading to sudden cardiac death. Our research is enhancing the understanding of the causal mechanisms of RyR2 channel dysfunction and underpins new approaches to tackle calcium-linked arrhythmias.
- PHD. in a relevant field
- Established expertise and a portfolio of research publications in whole cell and/or single channel electrophysiology or cellular physiology.
For more details on this post, the University environment as well as to apply please visit:
Closing date: 25 April 2019
We are an equal opportunity employer aiming for diversity in our workforce.
Swansea University is a registered charity No.1138342