Postdoctor/ Project Group Leader in Bioinformatics, Epigentics; Embryo Development; Aging

Postdoctor/ Project Group Leader in Bioinformatics, Epigentics; Embryo Development; Aging

Oslo University Hospital (OUS)

Oslo, Norway

Department of Molecular Medicine

Oslo University Hospital is Scandinavia´s largest hospital with more than 20,000 employees, and is a major contributor to biomedical research in Norway. A postdoctoral fellowship in epigenetic computational analysis is now available in the Dahl research group, located at the research section of the Department of Molecular Medicine. The Dahl Laboratory is seeking highly motivated postdoctoral research fellows to lead studies to understand epigenetic regulation and aberrations in 1) early embryo development and 2) in aging and rejuvenation. 
A (senior) postdoctoral fellow with a strong publication record will have the opportunity to be supported for carrier advancement towards becoming a project group leader and further towards a principal investigator position. 

The Dahl Laboratory is well positioned for conducting basic research using both mouse and patient material, as well as performing advanced clinical studies. Specific projects focus on the epigenetic reprogramming of early embryo development and its significance for human reproduction. An overarching theme is the understanding of mechanisms and epigenetic information in the passing of life from one generation to the next, building on our recent discoveries (Dahl et al., Nature 2016). Aging related projects have a focus on stem cell aging, rejuvenation after hematopoietic stem cell transplantation in healthy humans and cancer. We have a particular interest in the mechanisms of aging and rejuvenation. Dahl lab website: https://www.ous-research.no/dahl/


We are located in Oslo, the Norwegian capital, at campus Rikshospitalet adjacent to the large, idyllic forest/recreational area “Nordmarka”. Oslo offers fantastic opportunities for outdoor activities as well as urban life, and is ranked as one of the best cities in the world to live in. Go for a swim in the warm water of the Oslo fjord in the summer, paddle your kayak onto the waterfront Opera house, or hike and bike through the lush forest to your “own” secluded lake. Oslo truly has four seasons and allows one to experience the beautiful colors of the autumn, go skiing from mid December to mid March – enjoying the bright white winter, and be amazed by the awakening of the nature in the spring.

Tasks


  • The successful candidate will be involved in leading one or more well-funded projects, and in addition the candidate will have the freedom to develop his/hers own ideas into new projects.

  • The candidate is expected to be involved in study design and to perform analysis of genomics and epigenomics data from several cell types, such as embryos and purified cells from young and old inpiduals resulting from e.g. ChIP-seq, DNA methylation arrays, WGBS, RNA-seq, ATAC-seq, Hi-C etc. And if needed, the candidate is expected to be capable of implementing or developing new algorithms to carry out advanced analysis.

Qualifications


  • A strong computational and statistical background (PhD or similar) is required.

  • Previous experience with (epi)genomic data analysis and an understanding of biology will be considered an advantage.

  • Candidates with bioinformatics experience in short read DNA sequencing analysis and genome scale integrative analysis of diverse experimental datasets will be favored.

  • Potential candidates have completed a PhD degree in bioinformatics/genomics or computer science, or similar fields, with one or more publications in internationally well-renowned, peer-reviewed scientific journals.

  • Excellent English written and verbal communication skills are required.

Personal attributes


  • The candidate should be highly motivated and dedicated, and have a strong interest in scientific research.

  • The candidate should be able to work both independently as well as in the context of a team, and be well organized.

  • Good communication skills are required as the successful applicant is expected to interact closely with experimental biologists and physicians.

We offer


  • An ambitious and stimulating scientific environment with excellent opportunities for academic development

  • Full-time three-year position

  • Top modern and excellent lab facilities with a wide range of core facilities

  • Attractive salary according to the guidelines from the Norwegian Cancer Association and Oslo University Hospital

  • Favorable pension arrangements

  • Attractive welfare arrangements, with very affordable high-quality childcare available

  • Assistance with applying for a skilled worker work permit for residents outside the EU: https://www.udi.no/en/want-to-apply/work-immigration/skilled-workers/#link-816

Interested persons should submit the following documents: 
1) A concise, single-page application letter, including a summary of scientific work, future interests and motivation for applying. 
2) Curriculum vitae (summarizing education, positions and other qualifying activity). 
3) List of publications. (Submitted manuscripts may also be included). 
4) Copies of educational certificates with grades. 
5) Letter of recommendation or reference letter from previous supervisors/mentors is optional, but considered an advantage. 
6) Contact information of three references that must include former coworkers and supervisors (name, email address, affiliation, phone number and relation to the candidate). 


Only applications submitted through the formal recruitment website WebCruiter can be considered. 

Any questions regarding the position can be directed to:

Principal Investigator Dr. John Arne Dahl – j.a.dahl@medisin.uio.no

Senior postdoctoral fellow, MD PhD, Arne Søraas – arne.vasli.lund.soraas@rr-research.no

Please apply via recruiter’s website.

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