Postdoctoral Positions – Novel DNA and RNA Modifications in the Brain: Bioinformatics / Mass Spectrometry / Molecular Biology / Neurobiology

Postdoctoral Positions – Novel DNA and RNA Modifications in the Brain: Bioinformatics / Mass Spectrometry / Molecular Biology / Neurobiology

Chinese Institute for Brain Research

Beijing, China

Our Institute – CIBR

The Chinese Institute for Brain Research (CIBR), in Beijing, is a recently established Institute that is directly connected with China’s top Tsinghua and Peking Universities and with the prestigious Chinese Academies. CIBR creatively tackles fundamental questions in biological science, brain function and animal behavior. Research areas cover neurobiology, molecular biology, developmental biology, computational science, biotechnology and clinical studies. CIBR supports ambitious, cross-disciplinary and innovative projects within a collaborative and international environment and has state-of-the art facilities.

KOZIOL LABORATORY

The Koziol Laboratory focuses on a new exciting area of research: We discover and study novel DNA and RNA modifications and investigate their function in healthy and diseased brain.

We are a newly established, friendly, collaborative, dynamic and ambitious research group that nurtures independent thinking and welcomes trying novel, often unconventional ideas. Our English-speaking laboratory offers many opportunities for personal and professional development.

THE VACANCIES

We are currently recruiting highly motivated and qualified Post-Doctoral Scientists who are excited about science and keen to discover and study novel and not well characterized DNA and RNA modifications in the brain. Critical thinking, troubleshooting skills, developing own ideas, keen on learning, ability to work independently and collaboratively are essential. Post-Doctoral Scientists must hold a PhD degree.

We are recruiting multiple Post-Doctoral Scientists to address fundamental biological questions:

(1) What are the unknown molecular mechanisms that regulate DNA/RNA modifications and what is their role? The project will discover and allow us to study molecules and pathways that regulate DNA/RNA modifications in human and mouse neuronal cells. The candidate should possess a solid background in molecular biology/biochemistry.
(2) Where do novel DNA/RNA modifications occur within the genome/transcriptome and what is their function? The project involves the use of computational methods, such as PacBio/SMRT-Seq/MinION, to identify and study DNA and RNA modifications such as methylated deoxyadenosines within human and mouse genomes. The candidate should have demonstrable experience in data analysis from the Illumina sequencing platform. Experience in ChIP-Seq, RNA-Seq data analysis and knowledge of R for statistics is an advantage.
(3) How are DNA/RNA modifications distributed in healthy and diseased brains? Also, can we identify currently undiscovered DNA/RNA modifications in the brain? This project involves the systematic identification of DNA and RNA modifications in human/mouse brains by mass spectrometry. The candidate should be well organized, thorough and be interested in mass spectrometry. Experience with liquid chromatography, mass spectrometry or chemistry is an advantage, but is not a prerequisite.
(4) How do DNA/RNA modifications effect neuron and brain function? The goal of this project is to investigate the function of novel DNA/RNA modifications and their interacting proteins in the mouse brain. Prior experience with mice or in the field of neurobiology is an advantage.

In addition to the above projects, we of course always welcome applications with their own project ideas.

Comprehensive benefit packages and an international competitive salary of RMB 280k-350k (~40k-52k US$) per year will be provided, depending on experience and qualifications.

To Apply

Interested candidates should send a cover letter and CV to Magdalena Koziol, mjk@cibr.ac.cn. Please indicate which project you are applying for and provide contact details of 3 referees.

For additional information, please visit our websites at www.DNALaboratory.org and www.cibr.ac.cn.

For questions please contact Magdalena Koziol at mjk@cibr.ac.cn. Review of applications is ongoing and will continue until positions are filled. Earliest starting date is 1st June 2019.

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Postdoctoral Positions – Novel DNA and RNA Modifications in the Brain: Bioinformatics / Mass Spectrometry / Molecular Biology / Neurobiology